我国农村社区癫痫有效控制方案的推广性试验  

An Extended Study on "Conununity Control of Epilepsy" in Rural Areas of China

作　　者：王文志[1] 吴建中[1] 王太平 杨斌[3] 赵东海[1] 李建章[4] 徐志刚 

机构地区：[1]北京市神经外科研究所,100050 [2]山西省晋城市泽州县医院 [3]河南省焦作市人民医院 [4]河南医科大学第二附属医院

出　　处：《神经疾病与精神卫生》2002年第4期201-203,共3页Journal of Neuroscience and Mental Health

基　　金：国家科技部资助课题(专题号:96-920-06-05-30)

摘　　要：目的 探索适用于我国农村地区癫痫患者的有效治疗方法,并进一步验证其推广应用价值。方法 在山西晋城泽州县及河南焦作市武陟县两个农村社区人群中选定全身强直-阵挛型发作的活动性癫痫患者376人(山西185例,河南191例)。由经过短期培训的乡村医生按照规定方案使用苯巴比妥单药治疗、管理病人,并观察疗效、患者的依从性及药物不良反应。结果 治疗观察1年的效果表明,服药7～12个月期间与入组前半年的情况比较,有45.9％的患者未再发作,发作频度减少>75％者占15％,两项合计显效率为60.9％。在规定剂量内无明显副作用。结论 本研究再次证明,该方案适合在我国广大农村地区进一步推广应用,可使约半数癫痫患者受益。To expbre and evaluate the suitable and effective measures to control epilepsy at community level in rural areas of China. Methods 376 active epileptic patients with general -ized tonic - clonic seizures were selected in Zezhou county, Shanxi and in Wuzhi county, Henan province (185 from Shanxi, 191 from Henan). Patients were treated and managed by rural doctors who were trained about two days in Standard method of using Phenobarbital. Results The result of 12 months ob-servations revealed that 60. 9% of the patients got a good effect in which 45. 9% of them had no any seizure, 15% were reduced >75% on their seizure frequecy as compared with 6 months before entering the treated group, and no severe side- effects were found in the patients. Concluslons This study veri-fied again that the project of 'community control of epilepsy' proposed by WHO would suitably extend in rural areas of China, which can benefit about half of the patients with epilepsy.

关 键 词：癫痫 社区控制 苯巴比妥 农村地区 疗效 副作用 

分 类 号：R742.1[医药卫生—神经病学与精神病学]