双相情感性精神障碍躁狂相患者治疗前后微量元素的变化  

Comparative study of the changes of trace elements in patients with manic bipolar affective disorder

作　　者：常学润[1] 李智强[1] 李继敏[2] 戴婕 

机构地区：[1]山东省精神卫生中心,250014 [2]山东省荣军总医院 [3]济南医院

出　　处：《中国全科医学》2002年第8期616-617,共2页Chinese General Practice

摘　　要：目的　探讨双相情感性精神障碍躁狂相患者治疗前后微量元素的变化。方法　采用DCP -AES分析仪对 70例躁狂相患者和 72例健康对照者血清进行了 1 4种微量元素的测定。结果　 (1 )治疗前躁狂相患者与对照者的锰、铬、镉、镁、铝、钴、锂含量间的差别均有显著性意义 (P<0 0 5) ;(2 )躁狂相患者治疗前后血清锌、钴、锂、镉、铬含量间的差别有显著性意义 (P <0 0 5) ;(3)痊愈、近痊愈者与好转者的血清镉、铬、锂含量间的差别均有显著性意义 (P <0 0 5)。结论　躁狂相患者治疗前后微量元素的变化较明显 。Objective To explore the changes of the trace elements in the mania patients.Methods 14 kinds of trace elements were measured in the serum of the 72 patients and 70 normal persons by the DCP-AES analytical tool.Results (1)There were significant differences in the content of Mn,chrome,cadmium,Mg,Pb,Co and Li in the serum between the patients before the treatment and the control persons.(2) There were significant differences in the content of Zn,Co,Li,chrome and cadmium between before and after the treatment.(3)There were significant difference in the content of Li,chrome and cadmium between the cured patients and the improved patients.Conclusion The differences of the trace elements are significant between before and after the treatment in the mania patients.Its mechanism should be further studied.

关 键 词：双相情感性精神障碍 躁狂相 微量元素 治疗前 治疗后 

分 类 号：R749.41[医药卫生—神经病学与精神病学]