温热疗法对S180肿瘤模型治疗作用的实验  

Experimental study of hyperthermia on S180 tumor in mice

作　　者：孙诚[1] 柳霞[2] 黄鹤[1] 邓京京[1] 管晶[1] 

机构地区：[1]空军总医院放射科,北京100036 [2]空军总医院理疗科,北京100036

出　　处：《空军总医院学报》2002年第3期146-147,共2页Journal of General Hospital of Air Force,PLA

摘　　要：目的　观察温热疗法对小鼠 S180肿瘤模型的治疗效果。　方法　 30只 S180小鼠随机分 2组 :单纯热疗组 ,对照组 ,每组 15只。处理后 10 d处死动物 ,分离瘤块称湿重 ,并作病理检查。　结果　两组肿瘤湿重各为 (1.2 4± 0 .4 3) g和 (2 .31± 0 .2 2 ) g,热疗组肿瘤湿重显著低于对照组 (P<0 .0 1)。病理检查见热疗组肿瘤存在明显坏死。　结论　实验结果提示温热疗法具有较好的抗癌效果 。Objective To observe the anti tumor effects of hyperthermia on mice bearing S180 tumor. Methods 30 mice bearing S180 tumor were equally divided into 2 groups randomly: A group treated with hyperthermia and B group as contral group. The wet weight of tumor isolated from the mice and pathological change were evaluated and compared after 10 days. Results The wet weight of tumor in group A and B was (1.24±0 43) g and (2.31±0.22) g respectively. It was found that the wet weight of A group was less than that of the contral group. On pathological observation, it showed the widespread necrosis was much presented in A group. Conclusion The outcomes suggest that the hyperthermia has a better anti tumor effects on mice bearing S180 tumor. It can be as adjuvant therapy of cancer.

关 键 词：温热疗法 肿瘤模型 治疗 

分 类 号：R73－36[医药卫生—肿瘤]