脑垂体微腺瘤经蝶窦显微外科治疗——(120例临床分析)  

Microsurgical removal of pituitary microadenomas

作　　者：尹昭炎[1] 王维钧[1] 任祖渊[1] 苏长保[1] 阮伟峰[1] 史轶繁[2] 陆召林 金自孟[2] 臧旭[3] 

机构地区：[1]北京协和医院神经外科,100730 [2]北京协和医院内分泌科 [3]北京协和医院病理科

出　　处：《中华神经外科杂志》1991年第3期161-164,共4页Chinese Journal of Neurosurgery

摘　　要：本文报告经蝶窦显微外科治疗脑垂体微腺瘤120例,其中男20例,女100例,平均年龄31.7岁。视力视野正常,蝶窦大小都正常范围之内,垂体内分泌素测定皆高于正常。CT 扫描有不正常发现者65.4%,阴性者34.6%。肿瘤大小皆在10mm 之内。治愈率包括早年病例为46.6%,近3年已提高到81.2%,其中 ACTH 治愈率较高、GH 其次、PRL 较差,对脑垂体微腺瘤的诊断和疗效问题也加以讨论。120 pituitary microadenomas were removedtranssphenoidally by microsurgery in Peking UnionMedical College Hospital.There were 100 femalesand 20 males.Mean age was 31.7 yrs.Visualacuity and visual field showed normal in allpatients.The size of sella turcica all were withinnormal limit.CT scan of those patients werefound abnormal in 65.4%.negative in 34.6%cases.Pituitary hormone determination of thosepatients all were all over the normal range.Pathologically all tumors were less than 10 mmand the charater of the tumors were GH35,PRL42,ACTH 43 separately.Most of the GH and PRLadenomas were found from the surface of thehypophysis.More than 90% of ACTH adenomaswere located inside of pituitary gland.Cure rateincluding the early cases was 46.6%.Patientstreated in recent 3 years.the cure rate was81.2%.The diagnosis and therapeutic efficiencyare discussed also.

关 键 词：垂体肿瘤 经蝶窦 显微外科 

分 类 号：R736.405[医药卫生—肿瘤]