胰、胆、肝区癌组织间放射治疗  

Brachytherapy for the cancer of hepatoliliary and pancreatic area

作　　者：谢大业[1] 刘忠[1] 胡国平[1] 

机构地区：[1]宁波大学附属医院,浙江宁波200032

出　　处：《肝胆胰外科杂志》2002年第3期142-144,共3页Journal of Hepatopancreatobiliary Surgery

摘　　要：目的 :观察12 5碘 (12 5I)粒全封闭人工放射源组织间植入治疗肝胆胰区各类癌症的疗效。方法 :将12 5碘粒植入韧组织内治疗 15例累及肝胆胰区的癌症 ,其中 10例为胃癌累及胰腺及胃肝韧带 ,4例为转移性肝癌 (2例肠癌肝转移 ,1例乳癌肝转移 ,1例横纹肌肉瘤肝转移 )。男 9例 ,女 6例。年龄 :38～ 6 7岁 ,共植入12 5碘粒 5 6 6粒 ,平均每例 38粒。碘粒剂量为 0 .4 6～ 0 .8mci。结果 :15例均顺利渡过手术。粒子植入的放射野内 ,癌局部控制率为 90 % ,无放射并发症。结论 :组织间放疗与手术结合 ,可以缩小外科手术的解剖范围 ,扩大手术的治疗范围 。Objective:To observe the effect of 125 I seed capsulated in a welded titanium capsule on the treatment of patient with cancers involving the hepatoliliary and pancreatic area.Methods: 125 I seeds were inserted into the target tissue and permanently left there for brachytherapy in 15 cases inclucling 10 cases of gastric cancer involving pancreas,4 cases of metastatic liver cancer(2 cases of colou cancer,1 from breast cancer and 1 from rhatdomyosarcoma of abdominal wall),and 1 cancer of head of pancreas. Among them,a male and 6 female,their age ranging from 38 to 67. 5. 66 seeds were implanted with an average of 38 seeds per case. The dose of deed is 0.46～0.8 mci.Results:All cases were rehabilitated shorlly after operation,the local cancer control rate of the implanted lesions is about 90%. No radiation related complications or wandering seeds were found.Conclusion:Brachytherapy by implantation of 125 I seeds for cancers of hepatoliliary and pancreatic area has satisfactory outcome and tittle complication which gives surgeon the highest probability of abtaining improved result in the treatment of local disseminated or recurrent cancers.

关 键 词：^125碘粒 近距离放疗 肿瘤 放射疗法 胰腺癌 胆道癌 肝癌 

分 类 号：R735[医药卫生—肿瘤] R730.55[医药卫生—临床医学]