寒体和热体的实验研究(Ⅰ)  

Experimental Research on the Cold-Constitution and the Heat-Constitution(Ⅰ)

作　　者：张伟荣[1] 薛惠娟[1] 赵伟康[1] 匡调元[1] 顾文聪[1] 沈雁[1] 黄新生[1] 肖颐[1] 张俊[1] 陈国伟 

机构地区：[1]上海中医学院,上海200032

出　　处：《中西医结合杂志》1991年第8期477-479,共3页

基　　金：国家自然科学基金资助课题

摘　　要：本文依据匡调元提出的体质分型学说,对 Wistar 雄性大鼠筛选寒体与热体。并观察了寒体和热体在能量代谢与内分泌激素方面的差异。实验结果表明:寒体组大鼠在ADK 活性及细胞能荷。肝脏 Na^+-K^+-APTase 活性比热体大鼠低,另外 T_3、T_4、孕酮和睾酮含量方面也比热体大鼠低。可部分论证"体质病理学"一文提出的各型体质必然具有代谢上的差异。并且也提示今后在从事动物实验时应考虑到动物体质的因素。This paper reports the experimental research on the cold-constitution (CC) and the heat. constitution (HC).The authors have selected the CC and HC in Wistar rats,and have determined adenytate kinase(ADK) activities:energy charge and Na^+-K^+-ATPase activities in liver,the amounts of T_3,T_4,progesterone, testosterone and estradiol in serum,17-KS in urine.The ADK activities were markedly different between the HC group and the CC group (P<0.01).The Na^+-K^+- ATPase activities were obvious different between the HC group and the CC group(P<0.05).The energy charge of the HC group has increased by 16.1% as compared with the CC group in cells.The contents of T_3,T_4 of the HC group were higher than the CC group(P<0.01).The content of progesterone of the HC group was higher than the CC group as well(P<0.01).The contents of E_2 and 17-KS had no differences.These results indicated that differences between the CC and the HC were based on the basic metabolism and its regulators.

关 键 词：寒体 热体 腺苷酸激酶 细胞能荷 

分 类 号：R228[医药卫生—中医基础理论]