射频加温的临床热物理观察  

Clinical observation on thermophysics in radiofrequency heating

作　　者：祁超[1] 李鼎九[1] 郭保中[1] 石永刚[1] 杨道科[1] 

机构地区：[1]河南医科大学第一附属医院放射治疗科

出　　处：《中华放射肿瘤学杂志》2002年第3期208-211,共4页Chinese Journal of Radiation Oncology

摘　　要：目的　对NRL 0 0 1型深部热疗机物理特性进行研究。方法　采用NRL 0 0 1型深部热疗机对 15 1例患者进行 2对极板相互垂直交叉加热。热电偶测温点分别放置于直肠、耳膜、食管、瘤内或腹腔进行测温。结果　对测温系统准确性的研究结果显示 ,用水银温度计在停止治疗后测量与机测温度对比误差为 0 .1～ 0 .7℃。肺肿瘤内测温结果显示瘤内温度比全身温度高约 2℃。腹腔热盐水灌注后加温 ,腹腔内温度比直肠约高 0 .5℃。腹腔热盐水灌注后热疗 ,观察其温度的均匀性 ,发现随加温时间的延长腹腔温度渐趋向均匀 ,在约 5 0min后基本均匀 ;另外腹部按摩会缩短时间。结论　该机测温系统与标准水银温度计误差较小可以接受。在食管癌及腹腔热灌注加温时测耳温、食管、直肠温度可基本表达实际温度。肺部肿瘤局部热疗时食管腔内温度比肺肿瘤温度可能低 2 .0℃。局部加温时 ,治疗区可能比全身温度高 2 .0℃左右。腹腔热盐水灌注后加温方法可行 ,各处温度随时间延长趋于均匀。加温时间应该适当延长 ,推荐在 12 0min以上。在有条件时尽可能行瘤内测温 ,1次测温不代表该患者今后的情况。Objective To study the physical characters of NRL 001 heating machine. Methods 151 patients with deep seated tumors were heated by NRL 001 heating machine in the recent one year. NRL 001 heating machine with two pairs of perpendicular electrodes intercross the two magnetic fields at the center. thermocouples were placed in rectum, ear, esophageal lumen, tumor mass and peritoneal cavity for temperature measurement. The accuracy of the measurement system was evaluated by comparing the rectal mercury thermometer reading with the machine measured value right after the completion of heating. Results The deviation between the values read by rectal mercury thermometer and the machine was 0.1 0.7?℃. Intra tumoral measurement in a patient with lung carcinoma revealed that the temperature within the tumor was 2.0?℃ higher than that in the esophagus. When the peritoneal cavity was heated after perfusion with hot normal saline, the temperature in peritoneal cavity was 0.5?℃ higher than that in the rectum which became even with heating time. Temperature homogeneity was obtained after 50 minutes and abdominal massage was able to shorten this interval.Conclusions The temperature measurement system of NRL 001 heating machine, having acceptable discrepancies from the mercury thermometer, is reliable. The temperature in the ear, esophagus and rectum can be trusted when treating esophageal or peritoneo pelvic lesions. Temperature in the esophagus is 2.0?℃ lower than that in lung tumor. Temperature measured in the heated region is about 2.0?℃ higher than that over the whole body. Intra tumoral temperature measurement is highly recommended if possible. Peritoneo pelvic heating after peritoneal perfusion is feasible, with the temperature homogeneity obtained as heating time is prolonged, thereby heating time over 120?min is recommended. Temperature measurement is, in fact, necessary for every session of hyperthermia.

关 键 词：射频加温 腹腔热灌注 量热法 

分 类 号：R730.5[医药卫生—肿瘤]