结直肠癌术后腹腔免疫化疗的疗效观察  

Clinical observation on efficacy of the postoperative intraperitoneal immunochemotherapy on colorectal carcinoma.

作　　者：项明[1] 王天翔[1] 万亮[1] 朱上林[1] 

机构地区：[1]上海第二医科大学附属瑞金医院,上海200025

出　　处：《陕西肿瘤医学》2002年第3期177-178,共2页ShanXi Oncology Medicine

摘　　要：目的　观察腹腔免疫化疗在结直肠癌术后应用的疗效。方法　对 4 6例结直肠癌术后患者(DukesC期、D期 )行腹腔免疫化疗 ,评价患者生活质量、免疫指标改善 ,近期复发转移情况。结果　结直肠癌术后应用腹腔免疫化疗 ,患者免疫指标改善 ,副反应轻 ,术后肿瘤复发 ,转移率下降。结论　腹腔免疫化疗对防治结直肠癌术后复发 ,转移是一种安全。Objective To determine the effect of intraperitoneal(i.p.) immunochemotherapy in the postoperative management of colorectal carcinoma.Methods Forty-six postoperative patients with colorectal carcinoma(Duke's stage C or D) received i.p. immunochemotherapy. The quality of life, the improvement of immune level, and the state of recurrences and metastases were evaluated.Results The improvement of the immune level of the colorectal patients was observed after the postoperative use of i.p. immunochemotherapy. The side effects of the treatment were mild. And the postoperative recurrences and metastases decreased.Conclusion Intraperitoneal immunochemotherapy is a valuable modality to prevent the colorectal carcinoma from postoperative recurrence and metastasis.

关 键 词：疗效 腹腔化疗 免疫治疗 结直肠癌 复发 转移 

分 类 号：R735.35[医药卫生—肿瘤] R735.37[医药卫生—临床医学]