肝癌554例临床分析  

Clinical analysis on 554 patients with hepatocarcinoma.

作　　者：李福山[1] 李朝龙[1] 李黎波[1] 

机构地区：[1]第一军医大学南方医院,广州510515

出　　处：《陕西肿瘤医学》2002年第3期178-180,共3页ShanXi Oncology Medicine

摘　　要：目的　研究肝癌病变临床转化过程 ,分析肝癌死亡常见原因 ,探讨肝癌合理治疗模式 ,寻求肝癌有效预防和阻断方法。方法　总结分析 1999年度 5 5 4例肝癌临床资料 ,结合过去临床研究 ,讨论肝癌防治方法。结果　我国肝癌多在肝硬化等慢性肝病基础上发生 ,肝癌患者 92 6 %与乙肝病毒 (HBV)感染有关 ,其中 76 %表现抗HBe阳性 ,6 7 2 %曾有慢性肝炎病史 ,87 2 %合并肝硬化或肝纤维化 ,说明HBV感染可呈无症状携带者、急慢性肝炎 ,肝硬化和肝癌等不同病谱演变 ,肝癌是HBV持续感染者的最后结果和重要死因。资料表明引起肝癌患者死亡的原因往往是多方面的。结论　肝癌治疗以手术切除是较理想的治疗手段 ,介入治疗、聚能刀、光子刀、氩氦刀及超声聚焦刀等对缩小肿瘤亦有一定效果 ,但均不能彻底清除肿瘤 ,复发率较高。肝癌预防最有效方法是减少HBV感染机会。Objecttive Observating the clinical transformation process of primary liver cancer, analysing the common reason of primary liver cancer death,reasonable therapeutic pattern, and methods to prevent hepatocarcinoma Methods Combined previous clinical research, we summarized clinical data of 554 patients with liver cancer and discuss standpoints to prevent and treat hepatocarcinoma.Results Hepatocarcinoma is based on cirrhosis and other chronic hepatic diseases, 92.6% primary liver cancer patients are related to hepatitis B virus infection, among them, 76.0% patients are Anti-HBe positive, 67.2% once had chronic hepatitis history, and 87.2% patiets combined cirrhosis and liver fibrosis. HBV infection may show as carriers without sysmptom, acute and chronic hepatitis, cirrosis and hepatocarcinoma etc different variation of disease. Hepatocarcinoma is final outcome and important death reason of the patiets who infected by HBV continuously. This research showed that the reasons which cause hepatocarcinoma patients death are in many ways. conclusion primaryLiver cancer incidence rate is rather high in our country, and it seems to increase year by year. Operation is a rather ideal method to treat liver cancer. Intervention therapy, radiofrequency ablation, etc can decreased tumor size, but they can't clear cancer thoroughly, and relapse rate is high. The most effective method to prevent hepatocarcinoma is to reduce the HBV infected opportunity, stop the progression of HBV carrier, cure hepatitis and cirrhosis patients, and suppress the transformation to primary liver cancer. Only the pre-cancer interruption is able to prevent liver cancer.

关 键 词：肝癌 肝硬化 肝炎 癌变 预防 治疗 临床特征 

分 类 号：R735.7[医药卫生—肿瘤]