采用支付意愿模式评估偏头痛患者的负担  

An assessment of the burden of migraine using the willingness to pay model

作　　者：Hamelsky S.W. Lipton R.B. Stewart W.F. 夏峰 

机构地区：[1]Bristol- Myers Squibb, 1350 Liberty Avenue, Hillside, NJ 07205, United States Dr.

出　　处：《世界核心医学期刊文摘（神经病学分册）》2005年第6期18-18,共1页Digest of the World Core Medical Journals:Clinical Neurology

摘　　要：Willingness to pay methods measure treatment preferences and also measure the burden of illness in economic terms. We used a contingent valuation method to measure migraine sufferers’ willingness to pay (WTP) for acute medication for their most severe headache attacks, based on various profiles of treatment benefits and the characteristics of the migraine sufferer. Subjects were identified from a population- based database of migraine sufferers, previously recruited by random digit dialling. Telephone interviews (n = 1428) were used to gather demographic and headache characteristics. Subjects who met the International Headache Society criteria for migraine with or without aura and satisfied the other inclusion criteria based on telephone interview (n = 312) were invited to participate in a mailed questionnaire study. The questionnaire was mailed to the 310 subjects who agreed to participate and 201 (65% )- surveys were returned. The survey included questions on the demographics, the migraine characteristics, and the psychological disposition of the respondents. WTP for an acute migraine treatment with 14 different hypothetical treatment profiles was explored. Responders and non- responders to the survey were generally similar. The newly designed WTP questionnaire had high internal consistency (Cronbach’ s α 0.90) and test- retest reliability (Spearman’ s correlation coefficients 0.71- 0.77). Study subjects were willing to pay a median price of ＄ 5 for a migraine treatment that provided complete relief in 30 min and worked 100% of the time, with no side- effects and no headache recurrence. Median WTP decreased as treatment attributes deviated from this ideal. For example, WTP declined to a median of ＄ 1 for complete relief in 2 h and to ＄ 0.25 for complete relief in 4 h. All of the medication attributes powerfully influenced WTP. Several variables predicted WTP including current payment for medication, MIDAS (Grade III), and those with headaches of long duration. Subjects who employed a greater numberWillingness to pay methods measure treatment preferences and also measure the burden of illness in economic terms. We used a contingent valuation method to measure migraine sufferers’ willingness to pay (WTP) for acute medication for their most severe headache attacks, based on various profiles of treatment benefits and the characteristics of the migraine sufferer. Subjects were identified from a population- based database of migraine sufferers, previously recruited by random digit dialling. Telephone interviews (n = 1428) were used to gather demographic and headache characteristics. Subjects who met the International Headache Society criteria for migraine with or without aura and satisfied the other inclusion criteria based on telephone interview (n = 312) were invited to participate in a mailed questionnaire study. The questionnaire was mailed to the 310 subjects who agreed to participate and 201 (65% )- surveys were returned. The survey included questions on the demographics, the migraine characteristics, and the psychological disposition of the respondents. WTP for an acute migraine treatment with 14 different hypothetical treatment profiles was explored. Responders and non- responders to the survey were generally similar. The newly designed WTP questionnaire had high internal consistency (Cronbach' s α 0.90) and test- retest reliability (Spearman' s correlation coefficients 0.71- 0.77). Study subjects were willing to pay a median price of ＄ 5 for a migraine treatment that provided complete relief in 30 min and worked 100% of the time, with no side- effects and no headache recurrence. Median WTP decreased as treatment attributes deviated from this ideal. For example, WTP declined to a median of ＄ 1 for complete relief in 2 h and to ＄ 0.25 for complete relief in 4 h. All of the medication attributes powerfully influenced WTP. Several variables predicted WTP including current payment for medication, MIDAS (Grade III), and those with headaches of long duration. Subjects who employed a greater number of

关 键 词：偏头痛患者 支付意愿 模式评估 头痛发作 国际头痛协会 电话调查 药物治疗 统计学资料 数据库选择 评估法 

分 类 号：R747.2[医药卫生—神经病学与精神病学]