55例非交通性和交通性脑积水患者的B波客观分析  

Objective B wave analysis in 55 patients with noncommunicating and communicating hydrocephalus

作　　者：Stephensen H. Andersson N. Eklund A. M. Tisell 李一明 

机构地区：[1]Hydrocephalus Research Unit, Sahlgrenska University HosPital, Gteborg University, 413 45 Gteborg, Sweden Dr.

出　　处：《世界核心医学期刊文摘（神经病学分册）》2005年第10期28-28,共1页Digest of the World Core Medical Journals:Clinical Neurology

摘　　要：Background: B waves, slow and rhythmic oscillations in intracranial pressure (ICP), are claimed to be one of the best predictors of outcome after surgery for normal pressure hydrocephalus (NPH). Object: To determine the relation between the percentage of B waves and outcome in patients with hydrocephalus, and also t he diurnal variation of B waves. Methods: ICP and patient behaviour were recorde d overnight (17 to 26 hours) in 29 patients with non- communicating hydrocephal us and 26 with NPH. The B wave activity, measured with an amplitude threshold of 0.5, 0.75, 1.0, 1.5, 2.0, 3.0, and 5.0 mm Hg, was estimated as the percentage o f total monitoring time (% B waves) using a computer algorithm, and correlated with postoperative outcome, defined as changes in 12 standardised symptoms and signs. Results: There was no linear correlation between improvement after surger y in the 55 patients and total % B waves, but a correlation was found between improvement and % B waves during sleep (r=0.39, p=0.04). The percentage of B w aves was the same during sleep and wakefulness, and patients with NPH had the sa me proportion of B waves as the non- communicating patients. Conclusions: B wav es are commonly observed in patients with both communicating and non- communica ting hydrocephalus, but are only weakly related to the degree of postsurgical im provement.Background: B waves, slow and rhythmic oscillations in intracranial pressure (ICP), are claimed to be one of the best predictors of outcome after surgery for normal pressure hydrocephalus (NPH). Object: To determine the relation between the percentage of B waves and outcome in patients with hydrocephalus, and also t he diurnal variation of B waves. Methods: ICP and patient behaviour were recorde d overnight (17 to 26 hours) in 29 patients with non- communicating hydrocephal us and 26 with NPH. The B wave activity, measured with an amplitude threshold of 0.5, 0.75, 1.0, 1.5, 2.0, 3.0, and 5.0 mm Hg, was estimated as the percentage o f total monitoring time (% B waves) using a computer algorithm, and correlated with postoperative outcome, defined as changes in 12 standardised symptoms and signs. Results: There was no linear correlation between improvement after surger y in the 55 patients and total % B waves, but a correlation was found between improvement and % B waves during sleep (r=0.39, p=0.04). The percentage of B w aves was the same during sleep and wakefulness, and patients with NPH had the sa me proportion of B waves as the non- communicating patients. Conclusions: B wav es are commonly observed in patients with both communicating and non- communica ting hydrocephalus, but are only weakly related to the degree of postsurgical im provement.

关 键 词：交通性脑积水 客观分析 正常颅压脑积水 最佳预测 睡眠状态 振荡波 昼夜变化 计算法 线性相关 弱相关 

分 类 号：R742.7[医药卫生—神经病学与精神病学]