慢性炎症性脱髓鞘性多发性神经病患者膈神经的亚临床电生理学改变  

Subclinical electrophysiological alterations of phrenic nerve in chronic inflammatory demyelinating polyneuropathy

作　　者：Cocito D. Ciaramitaro P. Rota E. 史利利 

机构地区：[1]Dr.U.O. Neurofisiologia Clinica, Dipartimento di Neuroscien-ze, Università di Torino, Via Cherasco 15, 10126 Torino, Italy

出　　处：《世界核心医学期刊文摘（神经病学分册）》2005年第12期32-33,共2页Digest of the World Core Medical Journals:Clinical Neurology

摘　　要：Alterations of the phrenic nerve (PN) and pulmonary function tests (PFTs) have been described in patients with chronic inflammatory demyelinating polyneuropathy (CIDP). This study was aimed at assessing the relationship between PN and respiratory function in CIDP patients without clinical signs of respiratory failure. Bilateral PN and right median nerve conduction studies were carried out along with blood gas analysis and PFTs: maximal inspiratory pressure; maximal expiratory pressure; forced vital capacity. The amplitude of the compound muscle action potential of the PN was seen to be altered in 19/24 (79%) patients and latency in 22 (92%). Eighteen patients (75%) showed at least one abnormal PFTs or CO2 partial pressure value. Electrophysiological alterations of the PN were observed in a high percentage of the CIDP patients studied. No statistically significant correlation was observed between PN and PFTs alterations.Alterations of the phrenic nerve (PN) and pulmonary function tests (PFTs) have been described in patients with chronic inflammatory demyelinating polyneuropathy (CIDP). This study was aimed at assessing the relationship between PN and respiratory function in CIDP patients without clinical signs of respiratory failure. Bilateral PN and right median nerve conduction studies were carried out along with blood gas analysis and PFTs: maximal inspiratory pressure; maximal expiratory pressure; forced vital capacity. The amplitude of the compound muscle action potential of the PN was seen to be altered in 19/24 (79%) patients and latency in 22 (92%). Eighteen patients (75%) showed at least one abnormal PFTs or CO2 partial pressure value. Electrophysiological alterations of the PN were observed in a high percentage of the CIDP patients studied. No statistically significant correlation was observed between PN and PFTs alterations.

关 键 词：膈神经 亚临床 电生理学 最大吸气压 最大呼气压 用力肺活量 传导功能 正中神经 呼吸衰竭 功能测试 

分 类 号：R744[医药卫生—神经病学与精神病学]