局部使用米替福新治疗腿部鳞状细胞癌的皮肤转移灶  

Treatment of cutaneous metastases of a squamous cell carcinoma of the leg with topical miltefosine (Fren)

作　　者：Mahieu- Renard L. Richard M.- A. Dales J.- P. 王琼 

机构地区：[1]Service de Dermatologie, H.opital Sainte- Marguerite, 270, boulevard de Sainte- Marguerite, 13009 Marseille, France

出　　处：《世界核心医学期刊文摘（皮肤病学分册）》2005年第8期51-51,共1页Digest of the World Core Medical JOurnals:Dermatology

摘　　要：Introduction. Miltefosine (Hexadecylphosphocholine) is a chemotherapy, which when applied locally, has demonstrated efficacy in the treatment of cutaneous metastases of breast cancer. Case report. A 79 year- old woman developed recurrent in transit cutaneous metastases of a squamous cell carcinoma on her left leg. All lesions completely resolved after topical applications of miltefosine. Tolerance was excellent and the patient remained disease- free 24 months after the end of the treatment. Discussion. Miltefosine, which might prove to be a simpleandeffectivealternativefortheusuallyheavytreatments proposed, warrants further assessment in this context.Introduction. Miltefosine (Hexadecylphosphocholine) is a chemotherapy, which when applied locally, has demonstrated efficacy in the treatment of cutaneous metastases of breast cancer. Case report. A 79 year- old woman developed recurrent in transit cutaneous metastases of a squamous cell carcinoma on her left leg. All lesions completely resolved after topical applications of miltefosine. Tolerance was excellent and the patient remained disease- free 24 months after the end of the treatment. Discussion. Miltefosine, which might prove to be a simpleandeffectivealternativefortheusuallyheavytreatments proposed, warrants further assessment in this context.

关 键 词：米替福新 鳞状细胞癌 患者耐受性 胆碱磷酸 化疗药物 十六烷 

分 类 号：R739.96[医药卫生—肿瘤]