睑结膜MALT(黏膜相关淋巴样组织)淋巴瘤(法语)  

MALT(Mucosal Associated Lymphoid Tissue) lymphoma of the palpebral conjunctiva(Fren)

作　　者：Cauvain A. Delmer A. Godeau M.-J. V.Descamps 潘敏(译) 

机构地区：[1]Service de Dermatologie,Universit'e Denis-Diderot,Paris VII,Assistance Publique-H?opitaux de Paris,46,rue Henri Huchard,75018 Paris,France

出　　处：《世界核心医学期刊文摘（皮肤病学分册）》2006年第10期29-30,共2页Digest of the World Core Medical JOurnals:Dermatology

摘　　要：Background.MALT(Mucosal Associated Lymphoid Tissue)lymphomas of the conjunctiva belong to the extranodal marginal zone B-cell lymphomas.This site,while standard,is uncommon.Case-report.A pink papular tumor developed on the lower eyelid of a 59-year-old woman.Sarcoidosis was diagnosed 9 years earlier associated with mediastinal lymphadenopathy and erythema nodosum not requiring treatment.Histological examination yielded a diagnosis of conjunctival MALT lymphoma.No visceral involvement was demonstrated.Radiotherapy(30 Gy)induced a complete response.A remote lesion developed on the patient’s arm 18 months later.No other sites were found.Further radiotherapy(26 Gy)again induced complete remission.No new lesions were seen after 24 months of follow-up.Discussion.This case is interesting because of the association of a MALT lymphoma and previous sarcoidosis,described in the literature as “sarcoidosis-lymphoma syndrome”.Association of sarcoidosis with MALT lymphomais infrequent.Treatment of conjunctival MALT lymphoma is standardized.Radiotherapy offers excellent efficacy and is well tolerated at this site.Regular and long-term follow-up is required.Local and distant relapse can occur.Background.MALT(Mucosal Associated Lymphoid Tissue)lymphomas of the conjunctiva belong to the extranodal marginal zone B-cell lymphomas.This site,while standard,is uncommon.Case-report.A pink papular tumor developed on the lower eyelid of a 59-year-old woman.Sarcoidosis was diagnosed 9 years earlier associated with mediastinal lymphadenopathy and erythema nodosum not requiring treatment.Histological examination yielded a diagnosis of conjunctival MALT lymphoma.No visceral involvement was demonstrated.Radiotherapy(30 Gy)induced a complete response.A remote lesion developed on the patient's arm 18 months later.No other sites were found.Further radiotherapy(26 Gy)again induced complete remission.No new lesions were seen after 24 months of follow-up.Discussion.This case is interesting because of the association of a MALT lymphoma and previous sarcoidosis,described in the literature as “sarcoidosis-lymphoma syndrome”.Association of sarcoidosis with MALT lymphomais infrequent.Treatment of conjunctival MALT lymphoma is standardized.Radiotherapy offers excellent efficacy and is well tolerated at this site.Regular and long-term follow-up is required.Local and distant relapse can occur.

关 键 词：MALT 睑结膜 淋巴样组织 淋巴瘤 边缘带 红色丘疹 远隔部位 下眼睑 纵隔淋巴结 结节病 

分 类 号：R739.7[医药卫生—肿瘤]