杜塞酰胺导致未手术眼的脉络膜脱离  

Dorzolamide-induced choroidal detachment in a surgically untreated eye

作　　者：李晶明 Goldberg S Gallily R Bishara S Blumenthal E.Z 

机构地区：[1]Department of Oph-thalmolog y,Hadassah-Hebrew Univ.Medical Cen-ter,Jerusalem,Israel.Dr.

出　　处：《世界核心医学期刊文摘（眼科学分册）》2005年第1期15-16,共2页Digest of the World Core Medical Journals:Ophthalmology

摘　　要：Purpose Choroidal detachment is a known complication of topical hypotensive agents when use d to treat eyes sensi-tized by prior surgery.We document t he abrupt develop-ment of an extensive choroidal detachment after initiation of dorzolamide therapy in a surgically untreated eye with pri-mary open-angle glaucoma.Design Observational case re-port.Methods A 76-year-old woman wi th primary open-angle glaucoma and no history o f ocular surgery de-veloped a choroidal detachment 12hours after initiation of therapy with dorzolamide eye drops.Choroidal detachment was diagnosed clinically and confir med by echography.Results Withdrawal of the drug and in itiation of corticos-teroid drops resulted in prompt reso lution of the choroidal detachment.Conclusions Choroidal detachment can occur in surgically untreated eyes after u se of a topical carbonic anhydrase inhibitor.Purpose Choroidal detachment is a known complication of topical hypotensive agents when use d to treat eyes sensi-tized by prior surgery.We document t he abrupt develop-ment of an extensive choroidal detachment after initiation of dorzolamide therapy in a surgically untreated eye with pri-mary open-angle glaucoma.Design Observational case re-port.Methods A 76-year-old woman wi th primary open-angle glaucoma and no history o f ocular surgery de-veloped a choroidal detachment 12hours after initiation of therapy with dorzolamide eye drops.Choroidal detachment was diagnosed clinically and confir med by echography.Results Withdrawal of the drug and in itiation of corticos-teroid drops resulted in prompt reso lution of the choroidal detachment.Conclusions Choroidal detachment can occur in surgically untreated eyes after u se of a topical carbonic anhydrase inhibitor.

关 键 词：脉络膜脱离 降眼压药物 碳酸酐酶抑制剂 激素滴眼液 观察性 超声检查 

分 类 号：R775[医药卫生—眼科]