丹麦úrhus县2型糖尿病随机人群中视网膜病变的患病率  

The prevalence of retinopathy in an unselected population of type 2 diab etes patients from úrhus County,Denmark

作　　者：Hove M.N. Kristensen J.K. Lauritzen T. Bek T. 杨建刚 

机构地区：[1]Department of Ophtha lmology, úrhus University Hospital, DK-8000 úrhus C, Denmark

出　　处：《世界核心医学期刊文摘（眼科学分册）》2005年第2期8-9,共2页Digest of the World Core Medical Journals:Ophthalmology

摘　　要：Purpose: To determine the prevalence of diabetic retinopathy and the causes of visual impairment in an unselected population of type 2 diabetes patients, and to describe the risk factors for developing diabetic retinopathy in this populat ion. Methods: A total of 10851 type 2 diabetes patients were identified in the c ounty of úrhus. A representative sample of 378 patients underwent a routine ocu lar examination, including fundus photography. Blood pressure and serum haemoglo bin A1c, total cholesterol, high density lipoprotein cholesterol, triglyceride a nd apolipoprotein a were measured. Results: The prevalence of diabetic retinopat hy in the type 2 diabetes population was 31.5%. In all, 2.9%had proliferative diabetic retinopathy and 5.3%had clinically significant macular oedema. Of the latter, 8/20 (40%) were newly identified and had not yet been lasertreated. The re was a positive correlation between severity of retinopathy and duration of di abetes, HbA1c, systolic blood pressure and treatment with insulin. None of the p atients had social blindness (visual acuity< 0.1), but 15/378 (4.0%) had develo ped visual impairment (VA < 0.3). Conclusion: The prevalence of diabetic retinop athy and visual impairment in this unselected type 2 diabetes population was low er than anticipated from the existing literature,and causes other than diabetic retinopathy contributed significantly to the occurrence of visual loss. A substa ntial number of the patients with vision-threatening diabetic maculopathy had n ot been referred for timely photocoagulation treatment.Purpose: To determine the prevalence of diabetic retinopathy and the causes of visual impairment in an unselected population of type 2 diabetes patients, and to describe the risk factors for developing diabetic retinopathy in this populat ion. Methods: A total of 10851 type 2 diabetes patients were identified in the c ounty of úrhus. A representative sample of 378 patients underwent a routine ocu lar examination, including fundus photography. Blood pressure and serum haemoglo bin A1c, total cholesterol, high density lipoprotein cholesterol, triglyceride a nd apolipoprotein a were measured. Results: The prevalence of diabetic retinopat hy in the type 2 diabetes population was 31.5%. In all, 2.9%had proliferative diabetic retinopathy and 5.3%had clinically significant macular oedema. Of the latter, 8/20 (40%) were newly identified and had not yet been lasertreated. The re was a positive correlation between severity of retinopathy and duration of di abetes, HbA1c, systolic blood pressure and treatment with insulin. None of the p atients had social blindness (visual acuity< 0.1), but 15/378 (4.0%) had develo ped visual impairment (VA < 0.3). Conclusion: The prevalence of diabetic retinop athy and visual impairment in this unselected type 2 diabetes population was low er than anticipated from the existing literature,and causes other than diabetic retinopathy contributed significantly to the occurrence of visual loss. A substa ntial number of the patients with vision-threatening diabetic maculopathy had n ot been referred for timely photocoagulation treatment.

关 键 词：视网膜病变 RHUS 眼底照相 视力损害 黄斑水肿 眼科常规检查 光凝治疗 高密度脂蛋白 载脂蛋白 总胆固醇 

分 类 号：R774.1[医药卫生—眼科]