新加坡学龄儿童角膜厚度检测与联系  

Corneal thickness determination and correlates in Singaporean schoolchildren

作　　者：Saw S.-M. Siak J.-K. 王媛 

出　　处：《世界核心医学期刊文摘（眼科学分册）》2005年第4期41-42,共2页Digest of the World Core Medical Journals:Ophthalmology

摘　　要：PURPOSE. To determine the central cornea thickness (CCT) in Singaporean children and to examine the possible relationship between intraocular pressure (IOP) and other biometric factors and CCT. METHODS. This was a cross- sectional study. The subjects (n=652) were obtained from the Singapore Cohort Study of the Risk Factors for Myopia (SCORM). The subjects’ ages ranged from 9 to 11 years. There were 485 Chinese, 92 Malayan, and 75 Asian Indian children. Measurement procedures included air- puff tonometry, noncontact slit lamp optical pachymet- ry, cycloplegic autorefraction, and autokeratometry. RESULTS. The mean CCT was 543.6± 32.0 μ m. Chinese children had thicker corneas than Malayan or Indian children (P=0.002). The boys had thicker corneas than girls (P=0.011), but the mean difference was only 6.4 μ m. There was high correlation of CCT (r=0.98) and IOP (r=0.88) between right and left eyes. IOP was correlated with CCT (r=0.45, P < .0.001). In a multiple linear regression model, each millimeter of mercury of IOP was associated with a CCT difference of 5.90 μ m (95% confidence interval [CIAbstract, 4.98- 6.82). The radius of corneal curvature correlated with CCT (r=0.19, P < 0.001). The following parameters were not significantly (P > 0.05) associated with CCT: age, family income, father s education, axial length, and spherical equivalent. CONCLUSIONS. The mean CCT in Singaporean children aged 9 to 11 years was 543.6 μ m and showed ethnic and gender variation. CCT affected measured IOP and correlated weakly with corneal curvature. Compared with data in adults, a change in CCT was associated with a greater difference in measured IOP.PURPOSE. To determine the central cornea thickness (CCT) in Singaporean children and to examine the possible relationship between intraocular pressure (IOP) and other biometric factors and CCT. METHODS. This was a cross- sectional study. The subjects (n=652) were obtained from the Singapore Cohort Study of the Risk Factors for Myopia (SCORM). The subjects’ ages ranged from 9 to 11 years. There were 485 Chinese, 92 Malayan, and 75 Asian Indian children. Measurement procedures included air- puff tonometry, noncontact slit lamp optical pachymet- ry, cycloplegic autorefraction, and autokeratometry. RESULTS. The mean CCT was 543.6± 32.0 μ m. Chinese children had thicker corneas than Malayan or Indian children (P=0.002). The boys had thicker corneas than girls (P=0.011), but the mean difference was only 6.4 μ m. There was high correlation of CCT (r=0.98) and IOP (r=0.88) between right and left eyes. IOP was correlated with CCT (r=0.45, P < .0.001). In a multiple linear regression model, each millimeter of mercury of IOP was associated with a CCT difference of 5.90 μ m (95% confidence interval [CIAbstract, 4.98- 6.82). The radius of corneal curvature correlated with CCT (r=0.19, P < 0.001). The following parameters were not significantly (P > 0.05) associated with CCT: age, family income, father s education, axial length, and spherical equivalent. CONCLUSIONS. The mean CCT in Singaporean children aged 9 to 11 years was 543.6 μ m and showed ethnic and gender variation. CCT affected measured IOP and correlated weakly with corneal curvature. Compared with data in adults, a change in CCT was associated with a greater difference in measured IOP.

关 键 词：角膜厚度 角膜曲率半径 眼轴长度 自动验光仪 等量球镜 非接触眼压计 角膜曲率计 生物因素 光学厚度 队列研究 

分 类 号：R770.1[医药卫生—眼科]