两种不同硅凝胶人工晶体植入后后囊浑浊形成的3年随访  

Three-year follow-up of posterior capsule opacification with two different silicone intraocular lenses

作　　者：Sundelin K. Shams H. Stenevi U. 陈立军 

机构地区：[1]Department of Ophthalmology, Molndal's Hospital, S-431 80 Mlndal, Sweden Dr

出　　处：《世界核心医学期刊文摘（眼科学分册）》2005年第8期8-9,共2页Digest of the World Core Medical Journals:Ophthalmology

摘　　要：Purpose: To compare posterior capsule opacification (PCO) after cataract surge ry with implantation of two silicone intraocular lenses (IOLs) with different de signs. Methods: We carried out a prospective, clinical study of 116 patients ran domized to standardized phacoemulsification with implantation of CeeOnEdge (n=57 ) or SI40NB (n=59) IOLs. The follow-up period was 3 years. To evaluate PCO morp hologically, digital images were obtained and analysed using evaluation of poste rior capsule opacification computer software (EPCO). The neodymium:YAG (Nd:YAG) capsulotomy rate was recorded. Results: At 2 and 3 years, the eyes with SI40NB I OLs had significantly more PCO than those with the CeeOn Edge IOLs (p=0.00014 an d p=0.002). Nine Nd:YAG capsulotomies were performed in the SI40NB group and non e in the CeeOn Edge group. This difference was statistically significant (p=0.00 3). In some patients a regression of PCO was noticed and confirmed usingEPCO. St atistically less PCO was noted when the capsulorhexis rim was placed so that it covered all 360 degrees of the optic of the IOL. Conclusions: A clinically and s tatistically significant difference in PCO development between CeeOn Edge and SI 40NB IOLs at 2 and 3 years postoperatively was found. These findings support earlier studies indicating that a sharp edge of the opt ic is a more important factor in IOL design than IOL material in the prevention of PCO.Purpose: To compare posterior capsule opacification (PCO) after cataract surge ry with implantation of two silicone intraocular lenses (IOLs) with different de signs. Methods: We carried out a prospective, clinical study of 116 patients ran domized to standardized phacoemulsification with implantation of CeeOnEdge (n=57 ) or SI40NB (n=59) IOLs. The follow-up period was 3 years. To evaluate PCO morp hologically, digital images were obtained and analysed using evaluation of poste rior capsule opacification computer software (EPCO). The neodymium:YAG (Nd:YAG) capsulotomy rate was recorded. Results: At 2 and 3 years, the eyes with SI40NB I OLs had significantly more PCO than those with the CeeOn Edge IOLs (p=0.00014 an d p=0.002). Nine Nd:YAG capsulotomies were performed in the SI40NB group and non e in the CeeOn Edge group. This difference was statistically significant (p=0.00 3). In some patients a regression of PCO was noticed and confirmed usingEPCO. St atistically less PCO was noted when the capsulorhexis rim was placed so that it covered all 360 degrees of the optic of the IOL. Conclusions: A clinically and s tatistically significant difference in PCO development between CeeOn Edge and SI 40NB IOLs at 2 and 3 years postoperatively was found. These findings support earlier studies indicating that a sharp edge of the opt ic is a more important factor in IOL design than IOL material in the prevention of PCO.

关 键 词：晶体植入 后囊 硅凝胶 人工晶体 撕囊 计算机分析软件 数码摄像 外观设计 自然消退 

分 类 号：R779.66[医药卫生—眼科]