发现位于泪腺窝外的泪腺组织:临床和组织病理学结果比较  

Occurrence of lacrimal gland tissue outside the lacrimal fossa: Comparison of clinical and histopathological findings

作　　者：Alyahya G.A. Bangsgaard R. Prause J.U. Heegaard S. 司冰心 

机构地区：[1]Eye Pathology Institute, University of Copenhagen, Frederik V's Vej 11-1, DK-2100 Cop enhagen, Denmark Dr.

出　　处：《世界核心医学期刊文摘（眼科学分册）》2005年第8期17-17,共1页Digest of the World Core Medical Journals:Ophthalmology

摘　　要：Purpose: To analyse clinical referral diagnoses and the location of lesions wi th histologically verified lacrimal gland tissue occurring outside the fossa of the lacrimal gland. Methods: Sections of lesions excised from areas outside the fossa of the lacrimal gland containing lacrimal gland tissue on histological exa mination were collected from the files of the Eye Pathology Institute, Copenhage n, Denmark. Specimens spanned a period of 50 years. Sections were re-examined a nd referral data on location and clinical diagnosis were compared with histologi cal findings. Results: A total of 120 lesions were collected. Of these, 59 (49% ) consisted of prolapsed lacrimal gland. The remaining 61 (51%) lesions contain ed ectopic lacrimal gland tissue, either as part of a complex choristoma in 38 ( 32%) cases, or as solitary ectopic lacrimal gland tissue in 23 (19%) cases. Th e majority (97; 81%) of lesions had been located at the temporal epibulbar conj unctiva and included mainly prolapsed lacrimal gland and complex choristoma. The clinical referral diagnoses covered a wide spectrum of lesions. The most freque nt clinical diagnoses were non-specific tumour (35%), non-specific cyst (18% ) and dermoid (11%). Of the 61 lesions containing ectopic lacrimal gland tissue , only two had been preoperatively diagnosed as such and only two of the 59 lesi ons with prolapsed lacrimal gland had been correctly diagnosed. Conclusions: Pro lapsed palpebral lobe of the lacrimal gland was the most common lesion and, as e xpected, the prime location was the temporal conjunctiva. Despite this location, the referring clinical diagnosis was often wrong or non-specific. Surgeons see m to have been unaware of the various clinical manifestations of extrafossal gla ndular tissue, particularly when excising lesions in the upper temporal region o f the conjunctiva. Surgical intervention in this location may jeopardizethe excr etory ducts of the lacrimal gland and may consequently lead to dry eye and thus should be avoided when the typical clinicaPurpose: To analyse clinical referral diagnoses and the location of lesions wi th histologically verified lacrimal gland tissue occurring outside the fossa of the lacrimal gland. Methods: Sections of lesions excised from areas outside the fossa of the lacrimal gland containing lacrimal gland tissue on histological exa mination were collected from the files of the Eye Pathology Institute, Copenhage n, Denmark. Specimens spanned a period of 50 years. Sections were re-examined a nd referral data on location and clinical diagnosis were compared with histologi cal findings. Results: A total of 120 lesions were collected. Of these, 59 (49% ) consisted of prolapsed lacrimal gland. The remaining 61 (51%) lesions contain ed ectopic lacrimal gland tissue, either as part of a complex choristoma in 38 ( 32%) cases, or as solitary ectopic lacrimal gland tissue in 23 (19%) cases. Th e majority (97; 81%) of lesions had been located at the temporal epibulbar conj unctiva and included mainly prolapsed lacrimal gland and complex choristoma. The clinical referral diagnoses covered a wide spectrum of lesions. The most freque nt clinical diagnoses were non-specific tumour (35%), non-specific cyst (18% ) and dermoid (11%). Of the 61 lesions containing ectopic lacrimal gland tissue , only two had been preoperatively diagnosed as such and only two of the 59 lesi ons with prolapsed lacrimal gland had been correctly diagnosed. Conclusions: Pro lapsed palpebral lobe of the lacrimal gland was the most common lesion and, as e xpected, the prime location was the temporal conjunctiva. Despite this location, the referring clinical diagnosis was often wrong or non-specific. Surgeons see m to have been unaware of the various clinical manifestations of extrafossal gla ndular tissue, particularly when excising lesions in the upper temporal region o f the conjunctiva. Surgical intervention in this location may jeopardizethe excr etory ducts of the lacrimal gland and may consequently lead to dry eye and thus should be avoided when the typical clinica

关 键 词：病理学结果 泪腺窝 迷芽瘤 颞侧球结膜 睑部 病理研究 泪腺脱垂 临床诊断 特异性肿瘤 皮样囊肿 

分 类 号：R777.21[医药卫生—眼科]