99mTc甲氧基异丁基异腈(MIBI)显像与甲状腺癌远处转移的关系研究  

作　　者：侯振山[1] 张勇[1] 申勇萌[1] 苏桂香[1] 李静静[1] 

机构地区：[1]郑州市第三人民医院核医学科,河南郑州450000

出　　处：《临床医药实践》2010年第6X期663-664,共2页Proceeding of Clinical Medicine

摘　　要：目的:探讨甲状腺癌原发灶摄取和清除99mTc-MIBI的能力与其发生远处转移的关系。方法:80例甲状腺癌患者行99mTc-MIBI双十相甲状腺局部静态显像,利用感兴趣区技术,分别计算MIBI早期,延迟肿瘤与正常组织的放射性计数比值(T/N)及洗脱率。根据临床检查结果,将患者分为远处转移组(31例)和无远处转移组(49例),并对两组结果进行统计学分析。结果:远处转移组MIBI早期,延迟T/N和洗脱率分别为(2.92±0.97)%,(1.99±0.99)%和(34±5.91)%;无远处转移组分别为(1.74±0.78)%,(1.97±0.86)%和(13±4.21)%,远处转移组MIBI早期T/N和洗脱率均高于无远处转移组(P<0.05),两组间MIBI延迟T/N差异无统计学意义(P>0.05)。结论:99mTc-MIBI显像早期T/N及洗脱率与甲状腺癌的远处转移关系密切,有进一步深入研究的价值。Objective: To investigate the relationship between capacity of primary foci of thyroid cancer uptake and remove 99mTc-MIBI with distant metastasis.Methods:80 cases of thyroid cancer patients with 99mTc-MIBI double-phase thyroid gland 10 local static imaging,using regions of interest techniques,calculated separately MIBI early,delayed tumor and normal tissue radioactivity count ratio(T/N) and the washout rate.Based on the clinical examination results,patients were divided into distant metastasis group(31 cases) and non-distant metastasis group(49 cases),and two sets of results were statistically analyzed.Results:Early distant metastasis group,MIBI delayed T / N and elution rates were(2.92±0.97)%,(1.99±0.99)% and(34±5.91)%;Non-distant metastasis group were(1.74±0.78)%,(1.97±0.86)% and(13±4.21)%.Distant metastasis group MIBI early T/N and the washout rate were higher than those without distant metastasis(P<0.05),MIBI delayed between the two groups T/N difference was not statistically significant(P>0.05).Conclusion:It’s have closely relation between T/N and the elution rate and distant metastasis of thyroid cancer in 99mTc-MIBI early imaging,It’s the value for further in-depth study.

关 键 词：甲状腺肿瘤 转移 MIBI 

分 类 号：R736.1[医药卫生—肿瘤]