手术治疗宫颈癌23例的预后及相关因素分析  

Analysis of prognosis and prognostic factors in 23 cases of cervix carcinoma underwent surgery

作　　者：吴绮霞[1] 邝绮慈[1] 梁欣[1] 

机构地区：[1]开平市中心医院妇产科,广东开平529300

出　　处：《临床医药实践》2010年第6X期761-762,共2页Proceeding of Clinical Medicine

摘　　要：目的:探讨影响手术治疗宫颈癌患者预后的危险因素,为制定合理的临床干预方案提供依据。方法:回顾性分析2000年3月-2005年2月在我院手术治疗的23例宫颈癌患者的临床资料和预后,采用Cox比例风险模型对可能影响手术效果的风险因素进行分析。结果:本组5 a总体生存率为78.3%;单因素分析显示,肿瘤大小、临床分期、病理类型、肿瘤分化程度、深肌层浸润、盆腔淋巴结转移和手术类型与预后相关;多因素分析表明,临床分期、深肌层浸润、盆腔淋巴结转移和手术类型是影响预后的独立危险因素。结论:临床分期、深肌层浸润、盆腔淋巴结转移和手术类型与宫颈癌预后密切相关,在患者条件许可的情况下应尽可能达到R0切除。Objective:To investigate the prognostic factors of cervix carcinoma underwent surgery.Methods:Clinicopathologic data and prognoses of 23 cases of cervix carcinoma underwent surgery from March 2000 to February 2005 in our hospital were retrospectively analyzed.All possible prognostic factors were analyzed with the Cox proportional hazard model.Results:The 5-year overall survival rate was 78.3%.Cox univariate analysis showed that tumor size,tumor stage,pathological type,histological grade,depth muscular infiltration,cavitas pelvis lymph node metastasis and surgery modalities were related to prognosis.While multivariate analysis showed that tumor stage,depth muscular infiltration,cavitas pelvis lymph node metastasis and surgery modalities were independent prognostic factors.Conclusion:Tumor stage,deep muscular infiltration,pelvic lymph node metastasis and surgery modalities were closely related with the prognosis of cervix carcinoma.R0 resection should be obtained whenever possible.

关 键 词：宫颈肿瘤 外科手术 预后 危险因素 

分 类 号：R737.33[医药卫生—肿瘤]