64层^(18)F-FDG PET/CT在结肠癌N分期中的诊断价值(附73例报告)  

Diagnostic value of 64-slice spiral 18F-FDG PET/CT for lymph node metastasis incolon cancer

作　　者：任浩棠[1] 王毅均 李瑞平[1] 王立勇[1] 陈建新[1] 周建平[1] 

机构地区：[1]东莞市人民医院普外科一区,广东东莞523000

出　　处：《结直肠肛门外科》2015年第6期402-406,共5页Journal of Colorectal & Anal Surgery

摘　　要：目的评价64层^(18)F-FDG PET/CT在结肠癌N分期中的诊断价值。方法收集2013年5月至2015年1月收于我院就诊并手术的结肠癌患者73例,回顾性分析术前18F-FDG PET/CT检查结果与术后病理检查结果的一致性,并根据解剖学定位统计结肠癌区域的淋巴结转移情况。结果同机64层PET/CT诊断的灵敏度、特异度和准确率在4 mm时为80.2%、41.3%、56.7%;7 mm时为60.9%、87.3%、79.4%;10 mm时为30.2%、94.1%、76.2%;淋巴结最大标准摄取值(SUVmax)诊断的灵敏度、特异度和准确率在1.0时为100%、38.7%、54.9%;2.0时为91.3%、83.6%、85.1%;3.0时为77.9%、94.8%、90.9%。PET/CT在本次诊断结肠癌的准确率为100%,但与病理结果相比,PET/CT诊断淋巴结分期的准确率为90.4%。且当SUVmax在2.535时与病理结果诊断具有最高的一致性。结论 64层PET/CT检查能准确诊断结肠癌,并能清楚显示区域淋巴结情况,当取SUVmax在2~3之间时可以作为结肠癌N分期的评判标准,提高PET/CT在确定结肠癌术前分期的诊断准确性。Objective To evaluation the diagnostic value of 64-slice spiral 18F-FDG PET/CT for lymph node metastasis incolon cancer.Methods PET/CT and pathological findings of 133 patientswith colon cacer were retrospectively analyzed.Lymph node metastasis was recordedaccording to anatomical localization.Results Sensitivity,specificity,and accuracy of 64-slice PET/CT in the diagnosis for4 mm were 80.2%,41.3%,and56.7%,respectively;60.9%,87.3%,and79.4% for 7mm;and 30.2%,94.1%,and 76.2% for 10 mm.The sensitivity,specificity,and accuracy of lymph maximum standard uptake value(SUVmax) at 1.0 were 100%,38.7%,and54.9% respectively;91.3%,83.6%,and 85.1% at 2.0;and 7.9%,94.8%,and 90.9% at 3.0.In this study the diagnostic accuracy was 100% of PET/CT.However,accuracy rate for N metastasis was 90.4%.It was highly consistent with the pathological findings when SUVmax =2.535.Conclusion PET/CT has high diagnosis accuraty for colon cancer.It clearly shows lymph node metastasis.A cutoff SUVmax value of 2.0-3.0 can be the criteria for lymph node metastasis and improve the diagnostic accuracy.

关 键 词：结肠癌 18F-FDG PET/CT 临床诊断 

分 类 号：R735.35[医药卫生—肿瘤]