结直肠癌肝转移HIFU治疗的多因素回归分析(附146例临床报告)  

Cox regression analysis of factors related to colorectal cancer with liver metastasesreceiving HIFU

作　　者：刘黎[1] 周强[1] 黄国华[1] 毛英[1] 张匠 骆雯[1] 

机构地区：[1]遂宁市中心医院肿瘤科,四川遂宁629000

出　　处：《结直肠肛门外科》2015年第6期457-460,共4页Journal of Colorectal & Anal Surgery

摘　　要：目的对结直肠癌肝转移患者HIFU治疗后Cox多因素分析,了解各种因素对治疗效果及预后的影响。方法对HIFU治疗后的146例结直肠癌肝转移患者进行回顾性分析,建立Cox模型对预后产生影响的因素进行多因素分析。结果肿瘤大小、位置是结直肠癌肝转移HIFU治疗后局部控制率的影响因素(P<0.05),化疗、年龄、性别、分化程度、原发病灶位置对结直肠癌肝转移治疗后局部控制率的影响无统计学意义(P>0.05)。结论结直肠癌肝转移HIFU治疗后的疗效受多因素的影响,肿瘤大小是重要的影响因素。Objective To study the prognostic factors in patients with Colorectal cancer with liver metastasesreceiving HIFU using Cox proportional hazard model.Methods One hundred and fourty-six patients with colorectal cancer with liver metastaseswho recieved HIFU were retrospective analyzed.Risk factors were analyzed using Cox regression model analysis.Results Tumor size and location had significant influence on prognosis(P <0.05).Factors including chemotherapy,age,gender,primary tumor,grade of cell differentiation did not have significant influence on prognosis(P >0.05).Conclusion The efficacy of HIFU for colorectal cancer in patient with liver metastases were effected by multiple factors,among which tumor size was the most important factor.

关 键 词：结直肠癌肝转移 高能聚焦超声 

分 类 号：R735.34[医药卫生—肿瘤]