乳腺腺病、乳腺癌细胞核的DNA含量分析  

Study on DNA content in breast adenosis and carcinoma

作　　者：宫丽平[1,2] 师永红[1,2] 刘翠平[1,2] 苏光[1,2] 王玉芳[1,2] 

机构地区：[1]内蒙古医学院病理教研室 [2]内蒙古医学院第一附属医院内科及妇科

出　　处：《中国体视学与图像分析》1998年第4期253-255,共3页Chinese Journal of Stereology and Image Analysis

摘　　要：应用图像分析仪对４１例乳腺癌、４９例乳腺腺病及６例正常乳腺的组织细胞进行ＤＮＡ含量的测定。结果显示正常乳腺与１级腺病间ＤＮＡ含量无显著性差异（Ｐ＞００５），Ⅰ、Ⅱ级腺病及乳癌间均存在非常显著性差异。表明：ＤＮＡ含量的测定在Ⅰ、Ⅱ级腺病的判定及与乳癌关系研究中具有重要意义。对ＤＮＡ含量增加的腺病应警惕其癌变可能。DNA contents of 6 normal breast tissues,49 adenoses and 41 breast carcinomas were evaluated by means of image analysis system(Quantiment 970).DNA contents between normal breast tissues and grade 1 adenosis were similar but among grade Ⅰ,Ⅱadenosis and breast carcinoma significantly different.These results indicate estimation of DNA content may have important significance in studing the relationship between breast adenosis and carcinoma.We should be aware of the possibility of malignant transformation from adenosis with increasing DNA content.

关 键 词：乳腺癌 纤维囊性乳腺病 图像分析 DNA含量 

分 类 号：R737.9[医药卫生—肿瘤] R655.8[医药卫生—临床医学]