卵巢癌患者血清TGF-α、TNF-α水平检测的临床意义  

Detection of serum levels of Transfer growth factor (TGF)-α and Tumor necrosis factor (TNF)-α in patients with ovary carcinoma

作　　者：徐凤英[1] 曹传蕴[1] 

机构地区：[1]江苏省连云港市第一人民医院放免中心,222002

出　　处：《淮海医药》2002年第6期445-446,共2页Journal of Huaihai Medicine

摘　　要：目的　探讨血清 TGF- α、TNF- α在卵巢癌患者中的变化。方法　应用放射免疫分析法测定了 32例卵巢癌患者血清中 TGF-α、TNF-α含量 ,并与 35名正常健康人作对照。结果　卵巢癌患者血清中 TGF-α、TNF-α含量 ,显著地高于正常人和卵巢良性肿瘤组 (P<0 .0 1) ,后两组 TGF- α、TNF- α差异无显著性 (P>0 .0 5 )。结论　血清 TGF-α、TNF-α含量增高与卵巢癌相关。卵巢癌患者 TGF-α增高而Objective To explore the changes of serum TGF α and TNF α in patients with ovary carcinoma.Methods Serum TGF α and TNF α were detected by RIA in 32 patients with ovary carcinoma and 35 nomal controls.Results The levels of serum TGF α and TNF α were higher than those in nomal contros and patients with cytoadenoma( P <0.01),but no difference was found between the cytoadonoma and control group( P >0.05).Conclusion The higher levels of TGF α and TNF α might relate to the development of ovary carcinoma.The high level of TGF α and lower level of TNF α predict a poor prognosis for the patients.

关 键 词：卵巢肿瘤 转化生长因子Α 肿瘤坏死因子 放射免疫法 卵巢癌 

分 类 号：R737.31[医药卫生—肿瘤]