老年人脑血管病的纤溶活性观察  

Fibrinolytic Changes of Serum Fibrin(Fibrinogen)Degradation Products Level in Senile Patients with Cerebral Vascular Disorder

作　　者：张津[1] 丁铭臣[1] 

机构地区：[1]北京宣武医院神经内科

出　　处：《综合临床医学》1991年第6期288-290,共3页

摘　　要：本研究观察了老年人CVD 纤溶活性指标FDP 水平。采用间接血凝抑制方法测定病人组与同龄对照组的FDP,并比较了不同年龄组的健康人的纤溶状况。结果表明:老年CVD 病人FDP 增高显著,脑出血组高于脑梗塞组。而在健康人中,FDP 有一定程度的随龄改变,以50～59岁年龄组FDP 水平增高显著。此现象提示了血液高凝与高粘滞状态与增龄有关。Fibrin(fibrinogen)degradation Products(FDP)contribute to distur- bance of fibrinolysis and coagulation during cerebral is chemia and hemo- rrhage of adult patients.The Purpo- se of the present study is to deter- mine wether the abnormality of fib- rinolysis exist in senile patients with stroke evaluate the relation between fibrinolysis and age,we also tested the parameter in 135 he- althy persons with age range from 19—81 years old FDP of 37 patients with compl- ete stroke was compared to senile subject group(33 cases).In the gro- ups of stroke,the mean levels of FDP were higher than that in the senile control group.In addition, FDP level in the patient with cere- bral hemorrhage was much higher than those with cerebral infarction. Statistic value of variation analysis showed an increase of FDP in middle age(50-59 years)and a decrease in sinile healthy groups(60-69 and>70 years),compared to those of younger groups.the result indicate there is certain relationship between the cha- nges of FDP and the vascular deter- ioration in healthy elderly.

关 键 词：老年人 脑血管疾病 纤溶活性 

分 类 号：R743[医药卫生—神经病学与精神病学]