陈旧性眼化学伤角膜的形态学观察  

The morphologic investigation of corneas in eye-alkali wounds

作　　者：李永平[1] 冯官光[1] 冯春茂[1] 易玉珍[1] 林健贤[1] 

机构地区：[1]中山医科大学中山眼科中心卫生部眼科实验室,510060

出　　处：《中国眼耳鼻喉科杂志》2000年第2期20-21,共2页Chinese Journal of Ophthalmology and Otorhinolaryngology

摘　　要：目的:研究陈旧性眼化学伤角膜的形态学变化。方法:采用光镜、扫描电镜和透射电镜对70例眼化学伤角膜标本进行观察。结果:角膜上皮生长不良、血管形成、纤维增殖、炎症细胞浸润和角膜后膜形成为陈旧性眼化学伤角膜的主要病理改变。结论:角膜上皮细胞间距增宽,细胞间连接结构破坏,上皮下多层异常基底膜样物质,这些变化与临床上反复出现角膜上皮脱落有关。Purpose: To observe the morphologic changes of corneas in eye-alkali wounds.Methods: The corneas after keratoplasties in old eye-alkali burns were examined with light microscope,and electron microscope.Results: The main pathologic changes of corneas in old eye-alkali burns includes abnormal corneal epithlium,vascularization,proliferation of fibroblasts,inflammatory cells infiltration and the formation of retrocorneal membranes.Conclusion: The decrease of the junctions,the increase of intercellular spaces between the corneal epithalial cells and the multilayers and thickening basement membrane under the epithelium may be responsible for the clinical epithelial defects.The retrocorneal membranes were one of the important causes of the corneal rejection reaction after keratoplasties.

关 键 词：眼化学伤 角膜 电镜 

分 类 号：R779.1[医药卫生—眼科]