STERIC EFFECT OF THE REACTION OF 6,6-DIALKYLFULVENES WITH ALKYLLITHIUM AND METAL LITHIUM—SYNTHESIS OF SUBSTITUTED TITANOCENE DERIVATIVES  

作　　者：陈寿山 滑艳玲 雷致沛 

机构地区：[1]Institute of Elemento-Organic Chemistry,Elemento-Organic Chemistry Laboratory,Nankai University,Tianjin 300071,PRC

出　　处：《Progress in Natural Science:Materials International》1992年第2期143-150,共8页自然科学进展·国际材料（英文版）

基　　金：Project supported by the National Natural Science Foundation of China.

摘　　要：The steric hindrance effect of the reaction of 6,6-dialkylfulvenes and 6,6-polymethylene-fulvenes withethyllithium,n-butyllithium,i-butyllithium,cyclopentyllithium,cyclohexyllithium and metal lithium is brief-ly explored by the ~1HNMR of synthetical organotitanium compounds.For the reactions of fulvenes withalkyllithium,the exo-cyclic double bond addition,reduction,and the α-hydrogen abstraction from theside chain of the fulvenes take place.The reduction,reductive coupling and α-hydrogenabstraction reactions occur when metal lithium reacts with fulvenes.The reaction pattern depends on thedifference of the configuration and steric effect of substituents on 6-position of fulvenes andorganolithium.The steric hindrance effect of the reaction of 6,6-dialkylfulvenes and 6,6-polymethylene-fulvenes with ethyllithium,n-butyllithium,i-butyllithium,cyclopentyllithium,cyclohexyllithium and metal lithium is brief- ly explored by the ~1HNMR of synthetical organotitanium compounds.For the reactions of fulvenes with alkyllithium,the exo-cyclic double bond addition,reduction,and the α-hydrogen abstraction from the side chain of the fulvenes take place.The reduction,reductive coupling and α-hydrogen abstraction reactions occur when metal lithium reacts with fulvenes.The reaction pattern depends on the difference of the configuration and steric effect of substituents on 6-position of fulvenes and organolithium.

关 键 词：FULVENE addition reduction α-hydrogen ABSTRACTION 

分 类 号：N[自然科学总论]