中晚期胃癌腹腔、静脉双轨化疗防治术后复发转移的临床意义  

Clinical significance of postoperative two-approach chemotherapy in the prevention and treatment of gastric carcinoma recurrence and metastasis

作　　者：杨志鹏[1] 张为群[1] 那曼[1] 郭桂莲[1] 姚丽[1] 史新华[1] 

机构地区：[1]新疆维吾尔自治区人民医院,乌鲁木齐830001

出　　处：《中国肿瘤临床与康复》2002年第5期42-43,共2页Chinese Journal of Clinical Oncology and Rehabilitation

摘　　要：目的　探讨进展期胃癌手术切除后 ,血道、腹腔复发转移的防治方法。方法　对 42例进展期胃癌术后 ,第1天静脉表阿霉素 (吡柔比星 ) 60～ 90mg ,第 1、5天腹腔 5 Fu 1g ,CF 2 0 0mg ,CDDP 5 0mg投药 2次 ,第 2～ 3天CF/5 Fu通过电子泵连续 72小时静脉化疗 ,并对化疗后 1～ 3年生存率进行随访总结。结果　 42例病人实施腹腔、静脉双轨化疗后 ,1、2、3年生存率分别为 :88%、83 % ,5 2 .3 % ,且并发症与副反应较轻。结论　静脉、腹腔双轨化疗对进展期胃癌术后复发、转移有明显的防治作用。ObjectiveTo evaluate two-approach chemotherapy in the prevention of postoperative gastric carcinoma recurrence and mefastasis.Methods42 postoperative patients of progressive gastric cancer were treated by using two-appoach infusion chemotherapy,the regimen consisting of 5-Fu 1g CDDP 50mg,(THP)60～90mg,and CF/5-Fu was continuously infused.After chemotherapy,all the patients were followed up for a period of 1～3 years.ResultsThe 1-,2-,and 3- year survival rates were 88%,83% and 52.3%,respectively.ConclusionThe two-approach chemotherapy is effective in the prevention and treatment of postoperative gastric carcinoma recurrence and metastasis.

关 键 词：中晚期 胃癌 临床意义 术后复发 肿瘤转移 腹腔化疗 静脉化疗 

分 类 号：R735.2[医药卫生—肿瘤]