贝尔面瘫患者血浆内皮素的检测及临床意义  

The setermination of endothelin in patients with bell palsy and its significances

作　　者：宋建新 舒海荣[1] 吕红[2] 吴立莲[2] 

机构地区：[1]台州市中心医院耳鼻咽喉科,浙江台州318000 [2]咸宁医学院附属第一医院耳鼻咽喉科

出　　处：《临床耳鼻咽喉科杂志》2002年第10期535-536,共2页Journal of Clinical Otorhinolaryngology

摘　　要：目的:探讨内皮素(ET)在贝尔面瘫发病中的作用及其与预后的关系。方法:采用放射免疫分析法测定21例贝尔面瘫患者治疗前、后及正常者的血浆ET水平。结果:贝尔面瘫患者的血浆ET水平与正常人对比;治疗无效组血浆ET水平明显高于治疗好转组。结论:ET异常增高可引起微循环障碍,在贝尔面瘫发病中起着重要作用;检测ET水平可作为判断患者预后的一个有用指标。Objective:To detect the role of the plasma endothelin in the process of Bell palsy and its relationship to prognosis. Method: The plasma endothelin were respectively determined with radioimmunoassay in 21 patients with Bell palsy and 20 normal control subjects. Result: The patients who were suffering from Bell palsy exhibited a statistically significant P <0. 01) increase in the endothelin level compared with that in the 20 normal control subjects. A significantly higher level of the plasma endothelin was found in unsatisfactory recovery group compared with that in satisfactory recovery group. Conclusion: Endothelin may play an important role in the process of Bell palsy, and may be a useful marer for the assessment of prognosis to the patients.

关 键 词：贝尔面瘫 血浆 内皮素 临床意义 放射免疫分析法 预后 

分 类 号：R745.12[医药卫生—神经病学与精神病学]