奥美拉唑治疗老年人急性出血性胃炎的临床观察  

CLINICAL OBSERVATION OF THE THERAPEUTICAL EFFECTS OF OMEPRAZOLE IN ELDERLY PEOPLE WITH ACUTE HEMORRHAGIC GASTRITIS

作　　者：张金泉[1] 孙迪安[1] 

机构地区：[1]上海市黄浦区中西医结合医院,200010

出　　处：《老年医学与保健》2002年第3期173-175,共3页Geriatrics & Health Care

摘　　要：目的观察奥美拉唑治疗老年人急性出血性胃炎的临床疗效。方法62例急性出血性胃炎的老年患者在治疗前插入胃管,用冷生理盐水清洗积血后,留置观察胃内出血情况,然后随机分成两组。奥美拉唑组32例,用奥美拉唑针剂40mg加于5%GS或0.9%NS20ml中静脉注射(静注),5～10分钟注完,每日2次。法莫替丁组30例,用法莫替丁针剂20mg加于5%GS或0.9%NS20ml中静注,5～10分钟注完,每日2次。结果奥美拉唑组有效率为94%(30/32);法莫替丁组有效率为67%(20/30)。两组间比较有非常显著性差异(P<0.01)。结论奥美拉唑针剂静注是治疗老年人急性出血性胃炎的有效止血药物。Objective To study the the ra peutical effects o f omeprazole in elderly people with a cute hemorrhagic gastri tis.Methods Sixty -two elderly people with acute hemorrhagic gastritis were r ecruit ed,nasogastric tube lavage was performed by physioloical saline before t he therapy.Then all patients were randomly divided into two groups.Thirty -tw o patients with omeprazole group were treated with omeprazole injection 40mg with 5%glucose or 0.9%sodium chl oride in-jection 20ml,iv,within 5to 10minut es,bid.Thirty patients with famoti dine group were treated with famo tid ine injection 20mg with 5%glucose or 0.9%sodium chloride injection 20ml,iv,within 5to 10minutes,bid.Results The effective rates in omepraz ole and famotidine group were 94%(30/32),67%(20/30)respecti vely.To compare both group s,the difference was statistically significant (P <0.01).Conclusions Omeprazole injection is an effectiv e treatment for a cute hemorrhagic gastritis in elderly people.[

关 键 词：非甾体类抗炎药 奥美拉唑 治疗 老年人 急性出血性胃炎 临床观察 法莫替丁 

分 类 号：R573.3[医药卫生—消化系统] R969.4[医药卫生—内科学]