A Survey of Moniliformin Contamination in Rice and Corn from Keshan Disease Endemic and Non-KSD Areas in China  

作　　者：YU SHI-RONG LIU XING-JIE WANG YU-HUA AND LIU JIANG(Institute of Nutrition and Food Hygiene, Chinese Academy ofPreventive Medicine, Beijing 100050, China) 

出　　处：《Biomedical and Environmental Sciences》1995年第4期330-334,共5页生物医学与环境科学（英文版）

摘　　要：Keshan Disease (KSD) is an endemic heart disease and moniliformin (MF) has been suggested as one of the etiological factors. In this paper, thin layer chromatographic (TLC) and high pressure liquid chromatographic (HPLC) methods were used for the determination of MF in the rice and corn samples collected from KSD areas and non-KSD afeas.One hundred and twenty-three rice samples were analyzed and showed MF contamination in only 8 samples (KSD areas: 8.4% positive, non-KSD areas: 2.5% positive) ranging from 73.6 to 265.3 ng/g (mean concentration. KSD areas 156.3 ng/g, non-KSD areas 179.5ng/g) One hundred and four corn samples in KSD areas and non-KSD areas weredeterminated by HPLC method, 45.2% samples were contaminated with MF (KSD areas:81.4%, non-KSD areas: 19.7%) Ianging from 52.3 to 1116.0 ng/g (mean concentration:KSD areas 488.9 ng/g; non-KSD areas 457.4 ng/g). The results showed that the contamination of MF in grains were significantly different between rice and corn, but not between the grains from the KSD areas and non-KSD afeas, then casting doubt on the role of MF as an etiological factor of KSKeshan Disease (KSD) is an endemic heart disease and moniliformin (MF) has been suggested as one of the etiological factors. In this paper, thin layer chromatographic (TLC) and high pressure liquid chromatographic (HPLC) methods were used for the determination of MF in the rice and corn samples collected from KSD areas and non-KSD afeas.One hundred and twenty-three rice samples were analyzed and showed MF contamination in only 8 samples (KSD areas: 8.4% positive, non-KSD areas: 2.5% positive) ranging from 73.6 to 265.3 ng/g (mean concentration. KSD areas 156.3 ng/g, non-KSD areas 179.5ng/g) One hundred and four corn samples in KSD areas and non-KSD areas weredeterminated by HPLC method, 45.2% samples were contaminated with MF (KSD areas:81.4%, non-KSD areas: 19.7%) Ianging from 52.3 to 1116.0 ng/g (mean concentration:KSD areas 488.9 ng/g; non-KSD areas 457.4 ng/g). The results showed that the contamination of MF in grains were significantly different between rice and corn, but not between the grains from the KSD areas and non-KSD afeas, then casting doubt on the role of MF as an etiological factor of KS

分 类 号：R155.52[医药卫生—营养与食品卫生学] R542.3[医药卫生—公共卫生与预防医学]