溃疡性结肠炎患者血清一氧化氮检测及意义  

Investigation of Serum NO Levels in Patients With Ulcerative Colitis

作　　者：陈垦[1] 汤斌[2] 祝斌[1] 梁坚[1] 王婉梅[1] 

机构地区：[1]广东医学院附属医院,广东湛江524001 [2]广东医学院免疫教研室

出　　处：《中国医师杂志》2002年第10期1073-1075,共3页Journal of Chinese Physician

摘　　要：目的　研究血清中一氧化氮 (NO)在溃疡性结肠炎 (UC)中的作用和意义。方法　测定 33例UC患者及正常对照者 4 0例血清NO水平。结果　活动性UC患者血清中NO水平明显增高 ;并与病情的轻重有关 (P<0 0 5 )。结论　血清NO升高可作为溃疡性结肠炎检测的实验室指标。Objective To investigate action and significance of serum nitric oxide(NO) in patients with ulcerative colitis.Methods Levels of serum NO in active stage of 33 patients with ulcerative colitis and 40 healthy controls were detected.Results Levels of serum NO in patients with ulcerative colitis were significantly high and related to severe degrees of the disease (P<0.05).Conclusion Immune dysfunction exists in patients with ulcerative colitis, There are relationship between higher levels of serum NO and ulcerative colitis pathogenesis and elevation of serum NO level may be as an indicator of ulcerative colitis.

关 键 词：临床意义 溃疡性结肠炎 血清 一氧化氮 

分 类 号：R574.62[医药卫生—消化系统]