雷贝拉唑联用呋喃唑酮克拉霉素治疗Hp相关性消化性溃疡的效果观察  

Observation of the effect of rebeprazole combined with furazolidone and clarithromycin in the treatment of patients with Hp related peptic ulcer

作　　者：童雪霞 Tong Xuexia(Department of Gastroenterology,the People's Hospital of Luotian County 438600)

机构地区：[1]罗田县人民医院消化内科,438600

出　　处：《中国社区医师》2016年第18期60-61,共2页Chinese Community Doctors

摘　　要：目的:观察给予Hp(幽门螺杆菌)相关性消化性溃疡患者雷贝拉唑、呋喃唑酮及克拉霉素联合治疗的临床效果。方法:收治Hp相关性消化性溃疡患者170例,平分为两组,对照组给予奥美拉唑、呋喃唑酮及克拉霉素联合治疗,研究组给予雷贝拉唑、呋喃唑酮及克拉霉素联合治疗,比较两组的治疗总有效率及Hp根除率。结果:经快速尿素酶实验检查,研究组Hp根除率91.76%,高于对照组的81.18%;研究组治疗总有效率97.65%,明显高于对照组的82.35%,组间差异有统计学意义(P<0.05)。结论:雷贝拉唑、呋喃唑酮及克拉霉素的联合方案用于Hp相关性消化性溃疡患者的治疗中,具有Hp根除率高、临床疗效显著的特点。Objective:To observe the effect of rebeprazole combined with furazolidone and clarithromycin in the treatment ofpatients with Hp related peptic ulcer.Methods:170 patients with Hp related peptic ulcer were selected.They were divided into thetwo groups.The control group was given omeprazole,furazolidone and clarithromycin for treatment,while the study group was givenrebeprazole combined with furazolidone and clarithromycin for treatment.We compared the total effective rate and Hp eradicationrate between groups.Results:By rapid urease test,the Hp eradication rate of the study group was 91.76%,which was higher thanthat in control group of 81.18%.The total effective rate of the study group was 97.65%,which was significantly higher than that ofthe control group of 82.35% .The differences between groups were statistically significant(P<0.05).Conclusion:rebeprazolecombined with furazolidone and clarithromycin in the treatment of patients with Hp related peptic ulcer has the characteristics ofhigh eradication rate and remarkable clinical curative effect.

关 键 词：幽门螺杆菌 呋喃唑酮 克拉霉素 雷贝拉唑 奥美拉唑 

分 类 号：R573.1[医药卫生—消化系统]