艾司西酞普兰治疗焦虑症和抑郁症的效果观察  

Effect observation of escitalopram in the treatment of anxiety and depression

作　　者：朱敏[1] Zhu Min(Department of Geriatrics,Yunnan Province Psychiatric Hospital 650011)

机构地区：[1]云南省精神病医院老年病科,650011

出　　处：《中国社区医师》2016年第30期104-105,共2页Chinese Community Doctors

摘　　要：目的:观察艾司西酞普兰治疗焦虑症和抑郁症的效果。方法:收治抑郁症伴有焦虑症患者72例,随机分为观察组和对照组,各36例。观察组给予口服草酸艾司西酞普兰片,对照组给予口服米氮平片。利用HAMD、HAMA和TESS对草酸艾司西酞普兰片的疗效及不良反应进行评估。结果:观察组总有效率及治愈率与对照组相当(P>0.05);治疗前观察组HAMD和HAMA评分差异无统计学意义(P>0.05),治疗8周后两组HAMD和HAMA评分较治疗前差异均有统计学意义(P<0.05);观察组和对照组不良反应发生率差异无统计学意义(P>0.05)。结论:草酸艾司西酞普兰对抑郁症和焦虑症有良好疗效,不良反应少且轻,可对抑郁症和焦虑症患者推广治疗。Objective:To observe the effect of escitalopram in the treatment of anxiety and depression.Methods:72 patients withdepression and anxiety were selected.They were randomly divided into the observation group and the control group with 36 casesin each.The observation group was given oral escitalopram tablet.The control group was given oral mirtazapine tablet.The curativeeffects and adverse reactions were evaluated by using HAMD, HAMA and TESS.Results:The total effective rate and cure rate ofthe observation group were equivalent compared with the control group(P>0.05).Before treatment,the HAMD and HAMA scoresof the observation group had no significant difference(P>0.05).After 8 weeks of treatment,the HAMD and HAMA score of twogroups were significantly different compared with those before treatment(P<0.05).The incidence rates of adverse reaction had nosignificant difference between the observation group and the control group(P>0.05).Conclusion:Escitalopram has a good effect ondepression and anxiety,and the adverse reaction is less and light.It can be widely used in the treatment of patients with depressionand anxiety.

关 键 词：艾司西酞普兰 焦虑症 抑郁症 

分 类 号：R749[医药卫生—神经病学与精神病学]