嗅鞘细胞移植与P2X4受体介导的神经病理痛相关性研究进展  

Research Progress in Relationship between Olfactory Ensheathing Cell Transplantation and P2X4 Receptors-Mediated Neuropathic Pain

作　　者：张文俊[1] 况荣华[2] 刘曾旭[3] ZHANG Wen-jun;KUANG Rong-hua;LIU Zeng-xu

机构地区：[1]南昌大学研究生院医学部,2013级南昌330006 [2]南昌大学期刊社,南昌330006 [3]南昌大学基础医学院解剖学教研室,南昌330006

出　　处：《南昌大学学报（医学版）》2016年第3期89-91,共3页Journal of Nanchang University：Medical Sciences

摘　　要：神经病理痛发病机制相当复杂,是目前临床治疗的焦点问题,P2X4受体在神经病理痛发生中起到核心中介的作用。由于嗅鞘细胞具有在神经损伤修复方面的独特生物学特性,成为目前在神经病理痛方面最具有潜在的治疗手段。本文就嗅鞘细胞移植与P2X4受体介导的神经病理痛相关性研究进展作一综述。The pathogenesis of neuropathic pain is quite complex, and it is currently the focus of clinical treatment. P2X4 receptors play a key role in the occurrence of neuropathic pain. Because olfactory ensheathing cells have unique biological properties in nerve repair, olfactory ensheathing cell transplantation has now become a potential treatment for neuropathic pain. This paper reviews the relationship between olfactory ensheathing cell transplantation and P2X4 receptors-mediated neuropathic pain.

关 键 词：嗅鞘细胞 神经病理痛 移植 P2X4受体 

分 类 号：R741.02[医药卫生—神经病学与精神病学]