^(18)F-FDG PET/CT发现胸腺鳞癌并多发肝转移两例报告  

Application of ^(18)F-FDG PET/CT in diagnosis of thymic squamous cell carcinoma complicated with multiple hepatic metastases: report of two cases

作　　者：曹素娥[1] 焦举[1] 邹琼[1] 朱姝[1] 杨婷[1] 张勇[1] Cao Sue;Jiao Ju;Zou Qiong;Zhu Shu;Yang Ting;Zhang Yong(Department o f Nuclear Medicine, the Third Affiliated Hospital o f Sun Yat-sen University, Guangzhou 510630, China)

机构地区：[1]中山大学附属第三医院核医学科,广州510630

出　　处：《新医学》2016年第10期708-714,共7页Journal of New Medicine

摘　　要：胸腺鳞癌在临床较为罕见,^(18)F-脱氧葡萄糖(FDG)正电子发射型计算机体层摄像术/计算机X线体层扫描(PET/CT)应用于胸腺鳞癌亦较少报道。该文报告2例中老年男性患者,均因肝内多发转移灶行^(18)F-FDG PET/CT检查,发现胸腺病灶,病理均证实为胸腺鳞癌。2例患者的胸腺病灶体积均较大,形态不规则,密度不均,见密集钙化灶,轻至中度强化,放射性分布不均匀,实性成分FDG摄取较高,2例患者预后均较差。该2例患者的诊治提示,胸腺鳞癌的^(18)F-FDG PET/CT检查结果具有一定的特征性,可提供解剖及功能方面的信息。^(18)F-FDG PET/CT在胸腺鳞癌的诊断、鉴别诊断和预测复发、转移及预后方面具有潜在价值。Thymic squamous cell carcinoma is rarely encountered in clinical practice. Application of 18F-FDG PET/CT in the diagnosis of thymic squamous cell carcinoma has been seldom reported. In this paper,two middle-aged and elderly male patients received 18F-FDG PET/CT due to multiple hepatic metastases. Thymuslesions were identified and pathologically diagnosed as thymic squamous cell carcinoma. In both patients,the thymus lesions were characterized as large size, irregular morphology, heterogeneous density, intensive calcification, mild to moderate enhancement and uneven radioactive distribution. The solid substances had highuptake level of FDG. Two cases presented with poor clinical prognosis. The diagnosis and treatment of thesetwo patients prompted that thymic squamous cell carcinoma patients had specific 18F-FDG PET/CT characteristics, which provided data for anatomical and functional analyses. 18F-FDG PET/CT is of potential for the diagnosis,differential diagnosis, predicting the recurrence, metastasis and clinical prognosis of patients with thymic squamous cell carcinoma.

关 键 词：胸腺肿瘤 诊断 18F-脱氧葡萄糖 正电子发射型计算机体层摄像术/计算机X线体层扫描 

分 类 号：R736.3[医药卫生—肿瘤] R730.44[医药卫生—临床医学]