纳米羟基磷灰石对托槽粘接剂抗菌性及粘接强度的影响  

Antibacterial effects and tensile bonding strength of orthodontic adhesive containing nanohydroxyapatite

作　　者：李振霞[1,2] 陈婷婷[3] 李沛霖[1,2] 薛晶[1,2] 张强[3] LI Zhen-xia;CHEN Ting-ting;LI Pei-lin;XUE Jing;ZHANG Qiang(State Key Laboratory of Oral Diseases, Sichuan University, Chengdu 610041, China;West China School of Stomatology, Sichuan University, Chengdu 610041, China;Shenzhen Maternity & Child Healthcare Hospital, Shenzhen 518048, China)

机构地区：[1]四川大学口腔疾病研究国家重点实验室,四川成都610041 [2]四川大学华西口腔医学院,四川成都610041 [3]南方医科大学附属深圳市妇幼保健院口腔病防治中心,广东深圳518048

出　　处：《口腔疾病防治》2017年第2期93-96,共4页Journal of Prevention and Treatment for Stomatological Diseases

基　　金：深圳市科技基金(JCYJ20140414153916122)

摘　　要：目的研究纳米羟基磷灰石及二氧化钛对托槽粘接剂的抗菌性能及粘接强度的影响。方法在纳米二氧化钛改性的托槽粘接剂(Grengloo)中加入质量分数0%、10%、20%、30%的纳米羟基磷灰石,于离体前磨牙上粘接托槽,测量拉伸粘接强度与粘接剂残留量。粘接树脂制成的圆片试样与菌悬液共培养48 h,测定细菌活性与代谢。结果 2%二氧化钛不影响粘接剂的粘接强度且可提高粘接剂的抗菌性。10%纳米羟基磷灰石使粘接剂的粘接强度明显降低。四组粘接剂残留指数差异无统计学意义。纳米羟基磷灰石无明显抗菌性。结论纳米羟基磷灰石不能明显提高Grengloo托槽粘接剂的抗菌性,随着其含量的增加粘接强度明显降低。Objective To evaluate the tensile bonding strength(TBS)and antibacterial properties when an orthodon?tic adhesive was added with nanohydroxyapatite(nHAp).Methods Light cure orthodontic adhesive(Grengloo)wasblended with2%TiO2containing nHAp nanoparticles by0%、10%、20%、30%(w/w),while the control was not blendedwith nHAp.Brackets were bonded to extracted premolars by these new adhesives.TBS of5groups were determined,andthe adhesive remnant index(ARI)scores were assessed.Composite discs specimen were prepared,incubated with bacte?rial suspension for48h,and tested for antibacterial properties.Results No significant difference was found in ARI.The colony unit counts and lactate productionof the groups containing2%TiO2were significantly reduced.The colonyunit counts and lactate production were without relationship with nHAp.The tensile bonding strength drastically de?creased when containing more than10%nHAp.Conclusion nHAp might not enhance the antibacterial effects of Gren?gloo.

关 键 词：纳米羟基磷灰石 二氧化钛 托槽粘接剂 抗菌性 拉伸粘接强度 

分 类 号：R783.5[医药卫生—口腔医学]