Ⅲc及Ⅳ期卵巢上皮性癌患者行新辅助化疗及间歇性肿瘤细胞减灭术的预后分析  

Analysis of the prognosis of neoadjuvant chemotherapy and intermittent cytoreductive surgery in patients with stage Ⅲc and stage Ⅳ epithelial ovarian cancer

作　　者：骆岚[1] 杜雪莲[1] Luo Lan;Du Xuelian(Department of Gynaecology,Jining City First People's Hospital of Shandong Province 272000)

机构地区：[1]山东省济宁市第一人民医院妇科,272000

出　　处：《中国社区医师》2017年第5期36-37,39,共3页Chinese Community Doctors

摘　　要：目的:分析Ⅲc及Ⅳ期卵巢上皮性癌患者行新辅助化疗及间歇性肿瘤细胞减灭术的预后。方法:研究组给予新辅助化疗+肿瘤细胞减灭术(NACT组),对照组给予规范的初次肿瘤细胞减灭术+辅助化疗(无NACT组),比较两组患者的预后。结果:NACT组发生术后残留少(P<0.05),NACT组再行间歇性肿瘤细胞减灭术概率降低。结论:新辅助化疗未明显改善Ⅲc及Ⅳ期的卵巢上皮癌患者的预后,NACT组术后残留减少,肿瘤细胞减灭术的满意切除率增高,再行间歇性肿瘤细胞减灭术的概率降低,从而有利于患者改善生活质量。Objective:To analyze the prognosis of neoadjuvant chemotherapy and intermittent cytoreductive surgery in patientswith stageⅢc and stageⅣepithelial ovarian cancer.Methods:The study group was given neoadjuvant chemotherapy andcytoreductive surgery(the NACT group).The control group was given the standard primary cytoreductive surgery and adjuvantchemotherapy(the no NACT group).The prognosis of the two groups of patients were compared.Results:The NACT group had lesspostoperative residual(P<0.05).The probability of intermittent cytoreductive surgery again in the NACT group was reduced.Conclusion:Neoadjuvant chemotherapy not significantly improves the prognosis of patients with stageⅢc and stageⅣepithelialovarian cancer;the postoperative residual of the NACT group is reduced;the satisfactory resection rate of cytoreductive surgery isincreased;the probability of intermittent cytoreductive surgery again is reduced,which is beneficial to improve the life quality ofpatients.

关 键 词：新辅助化疗 Ⅲc及Ⅳ期卵巢上皮性癌 间歇性肿瘤细胞减灭术 预后 

分 类 号：R737.31[医药卫生—肿瘤]