轻度认知损害危险因素的临床研究  

Clinical study of risk factors in mild cognitive impairment

作　　者：莫霄云[1] 黄琛[1] 梁劲松[1] 

机构地区：[1]广西中医药大学第一附属医院,广西南宁530023

出　　处：《中医临床研究》2017年第3期122-124,共3页Clinical Journal Of Chinese Medicine

基　　金：广西壮族自治区教育厅科研项目基金;合同编号:200911LX224

摘　　要：目的:探讨轻度认知损害(Mild Cognitive Impairment,MCI)的危险因素。方法:对72例MCI患者(MCI组),与年龄和性别相匹配的认知正常老年人30例(对照组),通过颈部血管B超检测是否存在颈动脉粥样硬化,及检测血脂和同型半胱氨酸进行对比研究。结果:结果显示颈动脉粥样硬化、血脂和同型半胱氨酸在两组之间差异有统计学意义(P<0.01或P<0.05)。结论:颈动脉粥样硬化、血脂代谢紊乱及高同型半胱氨酸可能是MCI的血管危险因素。Objective:To investigate the risk factors in mild cognitive impairment(mild cognitive impairment,MCI).Methods:72patients with MCI(MCI group)and30cases of normal elderly people(control group),of whom the age and gender matched cognitively,were given neck vascular ultrasound detecting to detect carotid atherosclerosis,and testing of the blood fat and homocysteine of two groups were compared.Results:The results showed that carotid atherosclerosis,blood fat and homocysteine of two groups were significantly different(P<0.01or P<0.05).Conclusion:Carotid atherosclerosis,high blood lipid metabolism disorders and homocysteine may be vascular risk factors in mild cognitive impairment.

关 键 词：轻度认知损害 颈动脉粥样硬化 血脂 同型半胱氨酸 危险因素 

分 类 号：R749.1[医药卫生—神经病学与精神病学]