儿童嗜酸细胞性膀胱炎7例临床分析  

Eosinophilic cystitis in children: a report of 7 cases and literature review

作　　者：赵少聪[1] 刘玉峰[1] 王叨[1] 李白[1] 苏淑芳[1] 魏林林[1] ZHAO Shaocong;LIU Yufeng;WANG Dao;LI Bai;SU Shufang;WEI Linlin(First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan, China)

机构地区：[1]郑州大学第一附属医院,河南郑州450052

出　　处：《临床儿科杂志》2017年第4期304-306,310,共4页Journal of Clinical Pediatrics

摘　　要：目的探讨儿童嗜酸细胞性膀胱炎的临床、病理特点及诊断和治疗。方法回顾分析2012年至2016年收治的7例嗜酸细胞性膀胱炎患儿的临床资料,并复习相关文献。结果 7例患儿的中位年龄为9岁,临床表现为尿急、尿频、尿痛、血尿、下腹痛、夜间遗尿等。超声和CT检查示膀胱壁增厚和占位性病变。7例患儿通过膀胱活组织检查均符合嗜酸细胞性膀胱炎;6例患儿经药物治疗后在2个月内痊愈,另1例反复药物治疗1年痊愈。随访3个月~4年,排尿异常症状消失,影像学检查膀胱异常变化消失。结论儿童嗜酸细胞性膀胱炎为良性病变,与膀胱肿瘤的临床表现极为相似,确诊靠组织活检外,也可根据临床表现、实验室检查及治疗效果;治疗以激素、抗组胺、抗炎药物为主。Objective To explore the clinical and pathological features,diagnosis and treatment of eosinophilic cystitis inchildren.Method The clinical data of7patients with eosinophilic cystitis admitted from2012to2016were retrospectively analyzed,and the related literature were reviewed.Results The median age of the7patients was9years,and clinical manifestations were urgenturination,frequent micturition,odynuria,hematuria,abdominal pain and nocturnal enuresis.Ultrasonography and CT examinationshowed thickened bladder wall and space occupying lesions.All the7children received bladder biopsy,and pathology was consistent witheosinophilic cystitis.Six of them were cured after2months of drug therapy,and the other one was cured by repeated drug treatment for1year.All patients were followed up for3months to4years until the abnormal symptoms of voiding disappeared and the abnormal changesof bladder disappeared by imaging examination.Conclusion Eosinophilic cystitis in children is a benign lesion,having extremelysimilar clinical manifestations to bladder tumor.Without biopsy,the diagnosis of eosinophilic cystitis can also be made according to theclinical manifestation,laboratory examination and treatment effect.The treatment for this disease mainly includes hormone,antihistamineand anti-inflammatory drugs.

关 键 词：嗜酸细胞性膀胱炎 诊断 治疗 儿童 

分 类 号：R726.9[医药卫生—儿科]