吡拉西坦注射液和甘露醇治疗颅内肿瘤术后高颅内压的临床效果分析  

Clinical analysis of Piracetam Injection and mannitol in the treatment of intracranial hypertension

作　　者：龚铁逢 龚高新 王小东[1] Gong Tie-feng;Gong Gao-xin;Wang Xiao-dong(Department of cerebral surgery, Loudi Central Hospital, Loudi, Hunan, 417000, China)

机构地区：[1]娄底市中心医院脑外科,湖南娄底417000

出　　处：《当代医学》2017年第13期114-115,共2页Contemporary Medicine

摘　　要：目的分析比较吡拉西坦注射液和甘露醇治疗颅内肿瘤术后高颅内压的临床效果。方法选取66例颅内肿瘤术后高颅内压患者作为本次实验的研究对象,对66例患者实施计算机随机分组。对照组33例患者实施甘露醇治疗,实验组33例患者实施吡拉西坦注射液治疗,分析比较两组颅内肿瘤术后高颅内压患者的生活质量评分、不良反应发生率及临床疗效。结果对照组患者的总有效率(84.85%)和实验组(90.91%)比较差异无统计学意义;且实验组和对照组患者的生活质量评分、不良反应发生率比较差异无统计学意义。结论对颅内肿瘤术后高颅内压患者采取吡拉西坦注射液治疗,效果显著,且不良作用较小。Objective To analyze and compare the clinical effects of Piracetam Injection and mannitol in the treatment of intracranial tumor after high intracranial pressure.Methods A total of66patients with intracranial hypertension after intracranial surgery were selected as the subjects of this study.The patients were randomly divided into66groups.The control group of33patients with mannitol treatment,experimental group of33patientswith Piracetam Injection treatment,analysis of high intracranial pressure,quality of life score in patients with intracranial tumor were comparedbetween the two groups the incidence of postoperative adverse reactions and clinical efficacy.Results The patients in the control group thetotal efficiency(84.85%)and experimental group(90.91%)there was no significant difference between the experimental group and the control;and the quality of life score,patients with adverse reaction rate had no significant difference.Conclusion The treatment of Piracetam Injection,high intracranialpressure in patients with intracranial tumor after surgery has significant effect,and less adverse effect.

关 键 词：吡拉西坦 甘露醇 颅内肿瘤 术后高颅内压 临床效果 

分 类 号：R739.41[医药卫生—肿瘤]