腹腔镜胃癌根治术与开腹胃癌根治术的临床对比研究  

Clinical comparative research of laparoscopic radical gastrectomy and laparotomy radical gastrectomy

作　　者：陈康寿[1] 吴雄辉[1] 黄伟[1] CHEN Kang-shou;WU Xiong-hui;HUANG Wei(Department One of General Surgery, Zhanjiang City Central People’s Hospital, Zhanjiang 524037, China)

机构地区：[1]湛江中心人民医院普外一科,524037

出　　处：《中国现代药物应用》2017年第11期46-48,共3页Chinese Journal of Modern Drug Application

基　　金：湛江市科技计划项目(项目编号:2016C01017)

摘　　要：目的对比分析腹腔镜胃癌根治术与开腹胃癌根治术的临床疗效差异。方法 102例胃癌患者,按随机数字表法分为腹腔镜组和开腹组,每组51例。开腹组采用开腹胃癌根治术治疗,腹腔镜组采用腹腔镜胃癌根治术,术中严格坚持无瘤原则。对比两组术中和术后指标,包括淋巴结清扫数、手术时间、切口大小、术中出血量、住院时间、切缘瘤细胞阳性、术后镇痛药物使用。观察术后两组并发症发生情况。结果两组患者均无切缘瘤细胞阳性,比较差异无统计学意义(P>0.05)。腹腔镜组术后镇痛药物使用显著少于开腹组,手术时间、切口大小、住院时间短于开腹组,术中出血量少于开腹组,差异有统计学意义(P<0.05);两组淋巴结清扫数目比较差异无统计学意义(P>0.05)。腹腔镜组并发症发生率为9.80%(5/51),低于开腹组的25.49%(13/51),差异有统计学意义(P<0.05)。结论与开腹胃癌根治术相比,腹腔镜胃癌根治术同样满足胃癌肿瘤根治的要求,且创伤小、术后恢复快、并发症少,具有较高的临床应用价值。Objective To comparatively analyze difference in clinical effects by laparoscopic radicalgastrectomy and laparotomy radical gastrectomy.Methods A total of102patients with stomach cancer weredivided by random number table into laparoscope group and laparotomy group,with51cases in each group.Thelaparotomy group received laparotomy radical gastrectomy for treatment,and the laparoscope group receivedlaparoscopic radical gastrectomy for treatment.The principle of tumor-free was strictly followed in operation.Comparison was made on intraoperative and postoperative indexes,including lymph node dissection number,operation time,incision length,intraoperative bleeding volume,hospital stay time,positive incisal edge oncocyte,and postoperative analgesics administration,between the two groups.Observation was made on occurrence ofpostoperative complications in the two groups.Results There was no positive incisal edge oncocyte in thetwo groups,and their difference had no statistical significance(P>0.05).The laparoscope group had obviouslyless postoperative analgesics administration,shorter operation time,incision length,hospital stay time,andless intraoperative bleeding volume than the laparotomy group,and the difference had statistical significance(P<0.05).The difference of lymph node dissection number between the two groups had no statistical significance(P>0.05).The laparoscope group had lower incidence of complications as9.80%(5/51)than25.49%(13/51)in the laparotomy group,and their difference had statistical significance(P<0.05).Conclusion Comparingwith laparotomy radical gastrectomy,laparoscopic radical gastrectomy can not only meet the requirement ofradical treatment for stomach cancer,but also provide small trauma,rapid postoperative rehabilitation and fewcomplications.This method contains high value for clinical application.

关 键 词：腹腔镜胃癌根治术 开腹胃癌根治术 疗效 并发症 

分 类 号：R735.2[医药卫生—肿瘤]