米诺环素软膏与甲硝唑凝胶治疗牙周炎的疗效对比分析  

Comparative analysis on curative effect of minocycline ointment and metronidazole gel in the treatment of periodontitis

作　　者：王冬梅[1] WANG Dong-mei(Department of Stomatology, Xinxiang Medical College Third Affiliated Hospital, Xinxiang 453003, China)

机构地区：[1]新乡医学院第三附属医院口腔科,453003

出　　处：《中国现代药物应用》2017年第14期16-18,共3页Chinese Journal of Modern Drug Application

摘　　要：目的分析米诺环素软膏与甲硝唑凝胶治疗牙周炎患者的临床疗效。方法 56例牙周炎患者,按照随机数字表法分为研究组和参照组,每组28例。参照组患者应用米诺环素软膏治疗,研究组患者应用甲硝唑凝胶治疗,比较两组治疗效果。结果研究组牙周袋探诊深度(PD)和龈沟液指标均优于参照组患者,差异有统计学意义(P<0.05)。研究组总有效率为96.43%,高于参照组的67.86%,差异有统计学意义(P<0.05)。研究组患者牙龈指数(GI)及牙龈出血指数均小于参照组,差异有统计学意义(P<0.05)。结论米诺环素软膏与甲硝唑凝胶治疗牙周炎的临床疗效更佳,可显著改善患者各项临床数据以及GI、牙龈出血指数,值得临床推荐。Objective To analyze the clinical efficacy of minocycline ointment and metronidazole gelin the treatment of periodontitis patients.Methods A total of56periodontitis patients were divided by randomnumber table method into research group and control group,with28cases in each group.The control group wastreated with minocycline ointment,and the research group was treated with metronidazole gel.Therapeutic effectwas compared in two groups.Results The research group had better periodontal pocket probing depth(PD)andgingival crevicular fluid index than the control group,and their difference had statistical significance(P<0.05).The research group had higher total effective rate as96.43%than67.86%in the control group,and the differencehad statistical significance(P<0.05).The research group had lower gingival index(GI)and gingival bleeding indexthan the control group,and their difference had statistical significance(P<0.05).Conclusion Metronidazolegel shows better clinical efficacy for the treatment of periodontitis,and it can significantly improve the patient'sclinical data and GI,gingival bleeding index.So it is worthy of clinical recommendations.

关 键 词：牙周炎 米诺环素软膏 甲硝唑凝胶 临床疗效 

分 类 号：R781.42[医药卫生—口腔医学]