腹腔镜下新型腹膜后淋巴结清扫术对宫颈癌患者疗效及生存质量的影响  

Effect of a new type of retroperitoneal lymph node dissection on the efficacy and quality of life of patients with cervical cancer

作　　者：黄海伟[1] 谢虹[1] 马新[1] Huang Hai-wei;Xie Hong;Ma Xin(Zhangjiagang first people's hospital,Obstetrics and Gynecology,Zhangjiagang,Jiangsu,215600,China)

机构地区：[1]张家港市第一人民医院妇产科,江苏张家港215600

出　　处：《当代医学》2017年第23期41-44,共4页Contemporary Medicine

摘　　要：目的探讨腹腔镜下解剖式腹膜后淋巴结清扫术(RPLND)对宫颈癌患者疗效及生存质量的影响。方法选取行腹腔镜RPLND的35例宫颈癌患者为研究对象,按照随机分组原则将其分为观察组(18例)与对照组(17例)两组,观察组采用腹腔镜下解剖式RPLND,对照组采用腹腔镜下传统RPLND,对比两组手术时间、术中出血量、切除淋巴结数、术后并发症以及术后恢复情况。结果两组手术时间、术中出血量、术后拔尿管时间、术后排气时间以及术后并发症发生情况比较,差异均无统计学意义;观察组切除淋巴结总量为(25.42±6.27)个,明显高于对照组淋巴结总量(17.56±6.14)个,差异有统计学意义(P<0.05);观察组术后平均引流液总量为(1 017.59±1 302.37)m L,明显少于对照组术后平均引流液总量(2 208.26±1 546.27)m L(P<0.05);观察组与对照组主要术后并发症有发热、淋巴囊肿、下肢水肿以及深静脉血栓等,两组发生并发症情况比较,差异无统计学意义;观察组住院时间为(16.52±2.47)d,明显少于对照组住院时间(22.06±3.81)d(P<0.05);观察组EORTC2C30评分为(16.36±3.21)分,明显高于对照组EORTC2C30评分(14.28±2.47)(P<0.05)。结论腹腔镜下解剖式RPLND术野清晰,解剖层次清楚,清扫淋巴结彻底,恢复快,有利于提高宫颈癌患者生存质量,值得临床推广。Objective To investigate the effect of a new type of retroperitoneal lymph node dissection on the efficacy and quality of life of patientswith cervical cancer.Methods35cases of cervical cancer underwent laparoscopic RPLND as the research object,divided into the observationgroup(18cases)and the control group(17cases).The observation group treated with laparoscopic anatomical type RPLND,the control group treatedwith the traditional RPLND laparoscopic,compared two groups of operation time,resection lymph node number,the amount of intraoperative bleeding,postoperative complications and recovery.Results Two groups of operation time,intraoperative bleeding volume,extubation time,postoperativeexhaust time and postoperative complications were compared,there were no significant differences;The observation group total lymph noderesection was(25.42±6.27),significantly higher than the control group the total lymph node(17.56±6.14)(P<0.05);The patients in the observationgroup the total drainage fluid for the average(1017.59±1302.37)mL,significantly less than the average of the total drainage fluid after surgery inthe control group(2208.26±1546.27)mL(P<0.05);The occurrence of complications between the two groups,there was no statistically significantdifference;The observation group hospitalization time was(16.52±2.47)days,significantly less than the control group hospitalization time was(22.06±3.81)days(P<0.05);the observation group EORTC2C30score was(16.36±3.21),significantly higher than the control group EORTC2C30score of(14.28±2.47)(P<0.05).Conclusion Laparoscopic anatomical RPLND has the advantages of clear field,clear anatomy,thorough dissectionof lymph nodes and quick recovery,which is beneficial to improve the quality of life of patients with cervical cancer,and is worthy of clinical Comparisonresults of hospitalization time and the quality of life score between two groups application.

关 键 词：解剖式腹膜后淋巴结清扫术 腹腔镜 腹膜后淋巴结清扫术 宫颈癌 并发症 生存质量 

分 类 号：R737.33[医药卫生—肿瘤]