不同防治方法对龋病患儿口腔链球菌数量的影响  

Effect of different control methods on number of Streptococcus oralis in children with caries

作　　者：张玉杰[1] 赵晓军[1] 赵丽[1] 张雪飞[1] 张江畔 于静[1] 胡永权[1] ZHANG Yujie;ZHAO Xiaojun;ZHAO Li;ZHANG Xuefei;ZHANG Jiangpan;YU Jing;HU Yongquan(Department of Stomatology,the Second Hospital of Shijiazhuang,Shijiazhuang 050051,China)

机构地区：[1]石家庄市第二医院口腔科,石家庄050051

出　　处：《解放军预防医学杂志》2017年第5期471-473,共3页Journal of Preventive Medicine of Chinese People's Liberation Army

摘　　要：目的探讨不同防治方法对龋病患儿口腔链球菌细胞数量的影响。方法随机抽样法选取400名学龄前儿童为研究对象,根据不同防治方法将其分为对照组(健康宣教,222名)与观察组(氟防龋,178名),跟踪随访1年,间隔6个月行口腔检查1次,比较2组龋病新增率,并于防治前、防治后6个月、12个月、24个月通过实时荧光定量PCR法测定各组无龋病儿童链球菌细菌数量。结果观察组末次随访龋病新增率显著高于对照组(P<0.05);与防治前比较,2组无龋病儿童防治后6个月、12个月总链球菌、口腔链球菌数量均显著减少(P<0.05);与对照组比较,观察组防治后6个月总链球菌、口腔链球菌、唾液链球菌、变异链球菌数量显著少,差异有统计学意义(P<0.05);与对照组比较,观察组防治后24个月变异链球菌数量比较差异无统计学意义(P>0.05)。结论健康宣教、氟化物使用均能有效预防龋病发生,减少口腔链球菌细菌数量,其中氟防龋效果更明显。Objective To investigate the effect of different control methods on the number of Streptococcus oralis in children with caries.Methods Four hundred pre-schoolers were randomly selected as subjects and divided into the control group(health education,222children)and the observation group(fluoride prevention of decayed teeth,178children)according to different control methods.All the subjects were followed up for1year and received an oral examination every six months.The rate of new increase of caries was compared between the two groups,and the number of Streptococcocci in children without caries in both groups was determined by real-time quantitative PCR method before control and6months,12months,24months after control.Results At the end of the follow-up,the rate of new increase of caries in the observation group was significantly higher than that in control group(P<0.05).The number of total Streptococcocci and number of Streptococcus oralis in children without caries in both groups were significantly lower at6months and12months after control(P<0.05).Compared with the control group,the number of total Streptococcocci,Streptococcus oralis,Streptococcus salivarius and streptococcus mutans in the observation group was significantly smaller at6months after control(P<0.05)but there was no significant difference in the number of Streptococcus mutans between the two group at24months after control(P>0.05).Conclusion Both health education and use of fluoride prevention of decayed teeth can effectively prevent the occurrence of caries and reduce the number of Streptococcus oralis,but the effect of fluoride prevention of decayed teeth is better.

关 键 词：龋病 健康宣教 氟防龋 链球菌 

分 类 号：R780.1[医药卫生—口腔医学]