晚期妊娠合并急性淋巴细胞性白血病1例  

Acute lymphoblastic leukemia in third trimester of pregnancy:a case report

作　　者：杨帆[1] 施鹏飞[1] 谢亚萍[1] 徐颖[1] 李沂玮 钱申贤[1] YANG Fan;SHI Peng-fei;XIE Ya-ping;XU Ying;LI Yi-wei;QIAN Shen-xian(Hematology department, Hangzhou the first people’s hospital, Hangzhou 310000, China)

机构地区：[1]杭州市第一人民医院血液内科,浙江杭州310000

出　　处：《中国生化药物杂志》2017年第9期366-367,369,共3页Chinese Journal of Biochemical Pharmaceutics

基　　金：资助项目:杭州市科技计划重点专病专科项目(20140733Q12)

摘　　要：目的提高临床医生对妊娠合并急性白血病治疗的认识。方法回顾性分析2016年12月13日本院收治的1例妊娠合并急性淋巴细胞性白血病患者的诊疗过程并讨论其终止妊娠时机的选择。结果本例患者为28岁女性，停经32周+，确诊急性淋巴细胞性白血病，在地塞米松治疗2天后即行剖宫产一健康男婴，术后行常规化疗，治疗期间出现脑出血，手术病理明确有白血病中枢浸润，经抢救患者脱离生命危险，急性白血病完全缓解。结论早期手术终止妊娠后再行化疗是晚期妊娠合并急性白血病治疗的可行方案。Objective To improve the understanding of clinician’treatment of pregnancy with acute lymphoblastic leukemia.Method Toanalyze tretrospectively the diagnosis and treatment process of1case with acute lymphoblastic leukemia from December13,2016,and discussthe selection of the timing of termination of pregnancy.Results The patient was a28years old female.She was dignosed for acute lymphocyticleukemia in the third trimester.She bore a healthy baby boy in caesarean section after a dexamethasone treatment for two days.Then she recevied aseries of standard chemotherapy.But she suffered a cerebral hemorrhage during treatment,and surgical pathology made a definite dignosis of centralnervous system leukemia.Finally,She was out of danger after rescue.Conclusion Postoperative chemotherapy is a feasible option for the treatmentof acute leukemia after the termination of pregnancy.

关 键 词：急性淋巴细胞性白血病 妊娠 剖宫产术 化疗 

分 类 号：R733.71[医药卫生—肿瘤]