经皮肝胆管穿刺引流术加胆管支架置入术治疗恶性梗阻性黄疸  

Percutaneous transhepatic catheterizde drainage combined with expandable metallic biliary endoprosthesis in treating malignant obstructive jaundice

作　　者：沙俊峰[1] 安建立[1] 牛洪涛[1] SHA Jun-feng;AN Jian-li;NIU Hong-tao(Department of Interventional Therapy, First Hospital of Qinhuangdao ,Qinhuangdao 066000 , Hebei, China)

机构地区：[1]秦皇岛市第一医院介入治疗科,河北秦皇岛066000

出　　处：《川北医学院学报》2017年第4期540-542,共3页Journal of North Sichuan Medical College

基　　金：河北省秦皇岛市科技支撑项目(201502A168)

摘　　要：目的:探讨经皮肝胆管穿刺引流术(PTCD)加胆道支架置入术治疗恶性梗阻性黄疸(MOJ)的临床应用价值。方法:分析130例行PTCD加胆道支架置入术的MOJ患者的临床资料,进行临床观察。结果:手术技术成功率达97.7%;术后肝功能较术前明显改善(P<0.05);术后并发症有胆道感染、急性胰腺炎及支架脱落等,经治疗后均好转;17例患者因肿瘤进展及多脏器功能衰竭死亡,中位生存期8.7个月。结论:PTCD加胆道支架置入术治疗MOJ安全有效,但术后需注意并发症的预防与治疗。Objective:To explore the clinical application value of percutaneous transhepatic catheterizde drainage(PTCD)combined with expandable metallic biliary endoprosthesis in the treatment of malignant obstructive jaundice(MOJ).Methods:The clinical data of130patients with MOJ who received PTCD combined with expandable metallic biliary endoprosthesis were analyzed for clinical observation.Results:The surgical successful rate was up to97.7%,which improved significantly than operation before(P<0.05).The postoperative complications include bilary tract infection,acute pancreatitis and stent detachment,which were improved after symptomatic treatment.A total of17patients died of tumor progression and multi-organ failure,with median survival time being8.7months.Conclusion:PTCD combined with expandable metallic biliary endoprosthesis is safe in the treatment of MOJ,but the prevention and treatment of postoperative complications should be highly concerned.

关 键 词：恶性梗阻性黄疸 经皮肝胆管穿刺引流术 胆管支架 

分 类 号：R575[医药卫生—消化系统]