肝动脉栓塞化疗术联合经皮无水乙醇注射治疗少血供肝癌的疗效观察  

Therapeutic effect of transcatheter arterial chemoembolization combined with percutaneous ethanol injection on small donor liver cancer

作　　者：谢觉醒 罗雯 郏鹏[2] XIE Jue-xing;LUO Wen;JIA Peng(Department of General Surgery, Taizhou First People’s Hospital, Taizhou 318020, China;Department of Radiology, Taizhou First People’s Hospital, Taizhou 318020, China)

机构地区：[1]台州市第一人民医院普外科,浙江台州318020 [2]台州市第一人民医院放射科,浙江台州318020

出　　处：《中国生化药物杂志》2017年第11期195-197,共3页Chinese Journal of Biochemical Pharmaceutics

摘　　要：目的探索肝动脉栓塞化疗术联合经皮无水乙醇注射治疗少血供肝癌的疗效。方法选择2016年4月～2017年4月台州市第一人民医院肝胆外科所收治的36例少血供肝癌患者作为本文的研究对象，将所有患者随机分为实验组与对照组，每组18例。其中实验组患者在采用肝动脉栓塞化疗术联合经皮无水乙醇注射进行治疗，对照组中的患者仅仅采用肝动脉栓塞化疗术治疗。结果实验组中的患者的治疗有效率为83.33%，对照组中的患者的治疗有效率为44.45%，实验组明显优于对照组，具有统计学意义（P＜0.05）；实验组中有8名患者出现了明显的发热症状，对照组中患者有9名患者出现了发热症状，2组患者并发症比较差异无统计学意义；实验组中的患者有77.77%的指标出现了较好的变化，而对照组中患者只有66.67%的指标出现了较好的变化，实验组明显优于对照组，差异具有统计学意义（P＜0.05）；实验组中患者的1、2、3年生存率分别为83.33%（15/18）、66.67%（10/15）、45.45%（5/11），对照组中患者的1、2、3年生存率分别为61.11%（11/18）、36.36%（4/11）、28.57%（2/7），实验组中患者在生存时间明显优于对照组，差异具有统计学意义（P＜0.05）。结论肝动脉栓塞化疗术联合经皮无水乙醇注射治疗少血供肝癌效果显著。Objective To explore the effect of transcatheter arterial chemoembolization combined with percutaneous ethanol injection in the treatment of small blood donor liver cancer.Methods We selected36cases of blood supply from Hepatobiliary Surgery during April2016to April2017,Liver cancer patients as the object of this study,all patients were randomly divided into experimental group and control group,each group of18cases.The patients in the experimental group were treated with transcatheter arterial chemoembolization combined with percutaneous ethanol injection.The patients in the control group were treated with transcatheter arterial chemoembolization.Results The effective rate of treatment was83.33%in the experimental group and44.45%in the control group.The experimental group was significantly better than the control group,the difference was statistically significant(P<0.05).The experimental group and the control group had no obvious difference.The experimental group and the control group had no obvious difference of the patients with77.77%of the patients showed a good change in the target group,and only66.67%of the patients in the control group showed a better change in the patient's index,the experimental group was significantly better than the control group,the statistics were significantly different(P<0.05).The1,2,and3-year survival rates were83.33%(15/18),66.67%(10/15)and45.45%(5/11)in the experimental group,The1,2,and3year survival rates were61.11%(11/18),36.36%(4/11)and28.57%(2/7)respectively.The survival time of the patients in the experimental group was significantly better than that in the control group(P<0.05).Conclusion Transcatheter arterial chemoembolization combined with percutaneous ethanol injection is effective in the treatment of small blood donor liver cancer,which should be popularized in clinical practice.

关 键 词：肝动脉栓塞化疗术 无水乙醇 少血供肝癌 肝功能 

分 类 号：R735.7[医药卫生—肿瘤]