3D打印技术在颅内动脉瘤介入栓塞治疗中的应用  

The application of 3D printing technique in treatment of interventional embolization of intracranial aneurysm

作　　者：谭衍 边远[1] 陆弘盈[1] 汤树洪[1] 余松祚[1] TAN Yan(Department of Neurosurgery, Guigang City People's Hospital, Guigang 537100, China)

机构地区：[1]贵港市人民医院神经外科,广西贵港537100

出　　处：《中国医学装备》2017年第12期64-67,共4页China Medical Equipment

摘　　要：目的:探讨三维(3D)打印技术应用于颅内动脉瘤介入栓塞治疗的临床价值。方法:选取医院经颅脑CT血管造影(CTA)确诊的21例颅内动脉瘤患者,其中大脑中动脉瘤7例,大脑前交叉通动脉瘤8例,基底动脉瘤6例;采用3D打印技术构建颅内动脉瘤复合体3D模型,并与介入栓塞术前颅脑CTA结果进行对比分析。结果:3D打印技术与颅脑CTA相比,其长、宽和厚度测量值无明显变化,差异无统计学意义(t=0.03,t=0.07,t=0.08;P>0.05);3D打印技术测量动脉瘤血流动力学结果显示,血流速度由大到小依次为动脉流入道、动脉流出道、动脉瘤体部和动脉瘤顶端,而且动脉流入道的瘤内动压、血管壁面切应力均明显增高,具有显著差异。所有患者动脉瘤均得到完全夹闭,围术期未出现偏瘫、失语及癫痫等严重并发症及死亡病例。结论:3D打印技术应用于颅内动脉瘤介入栓塞治疗中,不仅能够直观掌握动脉瘤患者脑血管解剖特点,降低术后并发症发生率及手术风险,而且3D模型便于患者及家属直观了解病情,形成良好的医患沟通,且便于教学及学术交流的直观详解。Objective:To explore the clinical value of3D printing technique was applied in treatment of interventional embolization of intracranial aneurysm.Methods:21patients with intracranial aneurysm(7cases were arterial aneurysm of middle cerebrum,8cases were arterial aneurysm of anterior crossing of the brain,and6cases were basilar artery aneurysm)who were confirmed by using computed tomography angiography(CTA)were enrolled in the research.The3D printing technique was applied to construct the3D complexus model of intracranial aneurysm,and it was compared and analyzed with the CTA results of pre-operative brain of interventional embolization.Results:The differences of length,wide and thickness between3D printing technique and CTA of brain were no significant(t=0.03,t=0.07,t=0.08,P>0.05),respectively.The results of haemodynamics of arterial aneurysm that was measured by using3D printing technique indicated that the sequence of velocity of blood flowing from big to small was influx tract of artery,outflow tract of artery,body of artery aneurysm and the top of artery aneurysm.And both of intratumoral dynamic pressure of influx tract of artery and the wall shear stress of vessel were significantly increased.Besides,all of artery aneurysm were entirely clipped,and some serious complication included of hemiplegia,aphasia,epilepsy and death did not appeared at perioperative period.Conclusion:The application of3D printing technique in the treatment of interventional embolization of intracranial aneurysm not only can help doctors to intuitively grasp the anatomical features of blood vessel of brain in patients with arterial aneurysm and reduce the occurrence rate of complication and operative risk,but also can help patients and their family member to intuitively understand the disease state so as to establish better communication between doctors and patients.Besides,it also is convenient in the intuitive and particular explanation of the teaching and academic communication.

关 键 词：3D打印技术 颅内动脉瘤 介入栓塞 CT血管造影 

分 类 号：R739.91[医药卫生—肿瘤]